Evidence map›Paper›PMID 41571642›Full record

ArticleNature communications2026

Meta-unstable mRNAs in activated CD8

Paulo A Gameiro, Iosifina P Foskolou, Yumna A Butt, Aniek A M Martens, Klara Kuret Hodnik, Igor Ruiz de Los Mozos, Nordin D Zandhuis, Žan Hozjan, Veronica M Kot, Rupert Faraway and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Paulo A Gameiro *The Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.
Iosifina P Foskolou *Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, CB2 3EG, Cambridge, UK.ORCID http://orcid.org/0000-0003-1874-6356
Yumna A ButtMP Immunotherapy, Department of Research, Sanquin Blood Supply Foundation, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.ORCID http://orcid.org/0009-0005-4046-9502
Aniek A M MartensOncode Institute, 3521 AL, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0002-0291-0281
Klara Kuret HodnikNational Institute of Chemistry, Hajdrihova 19, 1001, Ljubljana, Slovenia.ORCID http://orcid.org/0000-0002-8445-8080
Igor Ruiz de Los MozosThe Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.ORCID http://orcid.org/0000-0003-4097-6422
Nordin D ZandhuisMP Immunotherapy, Department of Research, Sanquin Blood Supply Foundation, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.
Žan HozjanMP Immunotherapy, Department of Research, Sanquin Blood Supply Foundation, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.
Veronica M KotMP Immunotherapy, Department of Research, Sanquin Blood Supply Foundation, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.ORCID http://orcid.org/0009-0001-7195-7040
Rupert FarawayThe Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.
Michiel VermeulenOncode Institute, 3521 AL, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0003-0836-6894
Monika C WolkersMP Immunotherapy, Department of Research, Sanquin Blood Supply Foundation, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-3242-1363
Randall S JohnsonDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, CB2 3EG, Cambridge, UK. randall.johnson@ki.se.
Jernej UleThe Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK. jernej.ule@kcl.ac.uk.ORCID http://orcid.org/0000-0002-2452-4277

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) FP7/2007-2013/ERCEuropean Research Council 617837Wellcome Trust 103760Wellcome Trust (Wellcome) 103760/Z/14/Z
6 · The paper itself

Abstract

CD8

Indexed as

AdenosineAU Rich ElementsCD8-Positive T-LymphocytesLymphocyte ActivationRNA, MessengerRNA Stability3' Untranslated RegionsAnimalsEpitranscriptomeMiceMice, Inbred C57BLRNA-Binding ProteinsRNA MethylationTumor Necrosis Factor-alpha3' Untranslated RegionsAdenosineN-methyladenosineRNA-Binding ProteinsRNA, MessengerTumor Necrosis Factor-alpha

Identifiers

PMID41571642
PMCPMC12827480

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.