Evidence map›Paper›PMID 41571879›Full record

ArticleScientific reports2026

Pressure enhanced dual-solid-surface ultra-rapid cooling improves post-thaw recovery in hepatocytes and precision cut liver slices.

Mohammad Amini, James D Benson

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mohammad AminiDepartment of Mechanical and Mechatronics Engineering, Memorial University of Newfoundland, St. John's, A1B 3X5, Canada.
James D BensonDepartment of Biology, University of Saskatchewan, Saskatoon, S7N 5E2, Canada. james.benson@usask.ca.

Funding

National Science and Engineering Research Council RGPIN-2023-04007
6 · The paper itself

Abstract

Cell and tissue cryopreservation is essential in modern medicine for globally distributing biological materials; however, ice crystal formation hinders its efficacy. Non-equilibrium cryopreservation, which focuses on rapid cooling, shows promise in mitigating this issue and allows for reduced cryoprotective agent (CPA) concentrations, thereby minimizing cytotoxic effects. Increased pressure lowers both solution melting temperature (T

Indexed as

CryopreservationHepatocytesLiverAnimalsCell SurvivalCold TemperatureCryoprotective AgentsDimethyl SulfoxideHep G2 CellsHumansMicePressureVitrificationCryoprotective AgentsDimethyl SulfoxideCryopreservationGlass transitionHigh-pressurePCLSSolid-surface coolingVitrification

Identifiers

PMID41571879
PMCPMC12901298

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.