Evidence map›Paper›PMID 41571986›Full record

ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2026

AI in geriatric psychiatry: precision meets human experience.

Akiko Mizuno, Zackory Erickson, Daniel E Jimenez, Howard Jay Aizenstein

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Neuropsychiatric illness in the later years of life: summary and synthesis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Akiko MizunoDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. akm82@pitt.edu.ORCID http://orcid.org/0000-0001-5671-8044
Zackory EricksonDepartment of Robotics, Carnegie Mellon University, Pittsburgh, PA, USA.
Daniel E JimenezDepartment of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Howard Jay AizensteinDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0003-4897-6582

Funding

Vascular Moderators of the Impact of Alzheimer's Pathology in the Young-OldP01AG025204 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Ann D. Cohen · 2005 to 2026
$56.5M
TREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOPEZ, OSCAR L. · 1985 to 2019
$43.0M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
The University of Miami AIDS Research Center on Mental Health and HIV/AIDS - Center for HIV & Research in Mental Health (CHARM)Research Core & MHD-CEP30MH133399 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Victoria Behar-Zusman · 2023 to 2026
$8.9M
CLINICAL RESEARCH TRAINING IN LATE-LIFE MOOD DISORDERST32MH019986 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Carmen Andreescu · 1997 to 2026
$6.9M
AMYLOID PATHOLOGY AND COGNITION IN NORMAL ELDERLYR37AG025516 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLUNK, WILLIAM E · 2005 to 2014
$4.3M
Health Promotion in the Prevention of Anxiety and Depression: The Happy Older Latinos are Active (HOLA Study)R01MD012610 · NIMHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI JIMENEZ, DANIEL ENRIQUE · 2019 to 2023
$3.5M
Alzheimer’s Disease and Related Dementias in The Most Incarcerated Generation: An Understudied Population with Health DisparitiesR01AG082157 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BARRY, LISA C, BYERS, AMY LYNN · 2023 to 2025
$2.3M
Bioengineering in Psychiatry Training ProgramT32MH119168 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AIZENSTEIN, HOWARD J, IBRAHIM, TAMER S · 2019 to 2023
$1.1M
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) P30DK111024U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) P30MH133399U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) T32MH019986U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) T32MH119168U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) P01AG025204U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) P50AG005133U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R01AG082157U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R37AG025516U.S. Department of Health & Human Services | NIH | National Institute on Minority Health and Health Disparities (NIMHD) R01MD012610
6 · The paper itself

Abstract

Artificial intelligence (AI) and robotics are rapidly transforming geriatric psychiatry, offering powerful tools for early detection, personalized treatment, and enhanced care delivery. As the global population ages, these technologies promise not only greater efficiency but also new avenues for delivering scalable, accessible mental health support. However, as AI increasingly engages with domains once considered uniquely human-emotional intelligence, decision-making, and interpersonal connection-it raises deeper questions about the boundary between AI-simulated interaction and authentic human connection. This review examines the intersection of computational precision and existential complexity, emphasizing how theoretical frameworks such as the Theory of Computing (TOC) and Theory of Mind (ToM) can guide ethical and human-centered integration. While AI systems may convincingly simulate empathy or companionship, they cannot share subjective experience, vulnerability, or existential depth. By contrasting computational precision with the irreducible aspects of human complexity, we advocate for a transdisciplinary approach that embraces both the transformative potential of technology and the irreplaceable richness of human connection-especially in the later stages of life, when questions of purpose, mortality, and selfhood become most profound.

Identifiers

PMID41571986

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.