Evidence mapPaperPMID 41572155Full record

ReviewEuropean review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity2026

Relationship between body water distribution and sarcopenia in older adults: a systematic review.

Weslley Barbosa Sales, Laura Beatriz Alves Costa, Melissa Silva Rocha Pereira, Sabrina Gabrielle Gomes Fernandes Mâcedo, Edgar Ramos Vieira, Álvaro Campos Cavalcanti Maciel

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In one paragraph

Review in European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Weslley Barbosa SalesLagoa Nova, Natal - RN, Brazil, 59078-970, Federal University of Rio Grande do Norte, Natal, Brazil. weslleysaless8@gmail.com.
Laura Beatriz Alves CostaLagoa Nova, Natal - RN, Brazil, 59078-970, Federal University of Rio Grande do Norte, Natal, Brazil.
Melissa Silva Rocha PereiraLagoa Nova, Natal - RN, Brazil, 59078-970, Federal University of Rio Grande do Norte, Natal, Brazil.
Sabrina Gabrielle Gomes Fernandes MâcedoLagoa Nova, Natal - RN, Brazil, 59078-970, Federal University of Rio Grande do Norte, Natal, Brazil.
Edgar Ramos VieiraFlorida International University, Miami, USA.
Álvaro Campos Cavalcanti MacielLagoa Nova, Natal - RN, Brazil, 59078-970, Federal University of Rio Grande do Norte, Natal, Brazil.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

objectiveTo examine potential relationships between body water distribution, assessed by bioelectrical impedance analysis (BIA), and sarcopenia in older adults.

methodThis systematic review was conducted based on the methodological guidelines established by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Were Included observational studies exploring the relationship between intracellular water, extracellular water, and total body water – assessed by BIA and sarcopenia. The quality of the studies was assessed using the Joanna Briggs Institute (JBI) assessment tools and guidelines.

resultsInitially, 16,056 articles were identified, and 11 studies were considered eligible for inclusion. Among the studies analyzed, five studies used the ECW/TBW ratio, examining its association with aspects related to sarcopenia, such as muscle strength, loss of muscle mass and physical performance in the older adults. The results indicated that the proportions of extracellular/total body water (ECW/TBW) and extracellular/intracellular water (ECW/ICW) are associated with sarcopenia, muscle strength, loss of muscle mass, and physical performance in the older people. Studies suggest that these relationships may be useful for understanding muscle health and the impact of aging. Most studies presented high methodological quality (above 70%), indicating a low risk of bias.

conclusionsThe findings of this systematic review indicate that imbalances in body water distribution, particularly in the ECW/TBW and ECW/ICW ratios, are consistently associated with sarcopenia, loss of muscle mass, reduced strength, and poorer physical performance in the older adults.

Indexed as

Bioelectrical impedanceExtracellular waterIntracellular waterSarcopeniaTotal body water

Identifiers

PMID41572155
PMCPMC12922294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.