Evidence map›Paper›PMID 41572164›Full record

ArticleBMC gastroenterology2026

Diagnostic delay in children with coeliac disease: a national multicentre study in Turkey.

Yasin Sahin, Eylem Sevinc, Fatma Ilknur Varol, Ulas Emre Akbulut, Nevzat Aykut Bayrak, Aysegul Bukulmez

Abstract readMulticenter Study
In one paragraph

Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yasin SahinDepartment of Pediatric Gastroenterology, Dr. Ersin Arslan Training and Research Hospital, Gaziantep, 27560, Turkey. ysahin977@gmail.com.ORCID http://orcid.org/0000-0002-7394-4884
Eylem SevincDepartment of Pediatric Gastroenterology, Faculty of Medicine, Karabuk University, Karabuk, 78100, Turkey.ORCID http://orcid.org/0000-0003-1778-6559
Fatma Ilknur VarolDepartment of Pediatric Gastroenterology, Faculty of Medicine, Inonu University, Malatya, 244280, Turkey.ORCID http://orcid.org/0000-0001-5212-218X
Ulas Emre AkbulutDepartment of Pediatric Gastroenterology, University of Health Sciences, Antalya Training and Research Hospital, Antalya, 07100, Turkey.ORCID http://orcid.org/0000-0002-5098-4787
Nevzat Aykut BayrakDepartment of Pediatric Gastroenterology, Zeynep Kamil Women and Children's Training and Research Hospital, University of Health Sciences, Istanbul, 34668, Turkey.ORCID http://orcid.org/0000-0002-5553-6123
Aysegul BukulmezDepartment of Pediatric Gastroenterology, Afyonkarahisar Health Sciences University, Afyonkarahisar, 03030, Turkey.ORCID http://orcid.org/0000-0002-6013-5172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere are few studies conducted investigating diagnostic delay in children with coeliac disease (CD). A better understanding of the factors associated with diagnostic delay and the development of strategies to reduce it are important in preventing long-term complications related to the disease. This study aimed to determine the median diagnostic delay in children with CD and to investigate possible underlying factors associated with diagnostic delay.

methodsA prospective screening program was performed in children with CD at the seven clinical centers operating in Turkey within the Focus IN CD project between June 2021 and June 2023. Paediatric gastroenterologists were asked to complete a web-based questionnaire about CD.

resultsThe median age of the 188 children with CD (66 male; 35%) was 8.33 years (IQR: 5.02-13.00). The median diagnostic delay was 7.30 months (IQR: 2.73–15.50). Among the 188 patients included in the study, 172 (91.5%) were diagnosed within the first three years, whereas 16 (8.5%) were diagnosed after three years, and 68.7% of these patients had classical CD symptoms. Patients with CD were categorised according to the OSLO criteria. The median delay for the classic CD group, the nonclassic CD group and the silent CD group were found to be 7.63 (IQR: 3.13–16.06), 4.40 (IQR: 1.76–13.20) and 2.21 (IQR: 1.03–16.14) months, respectively. There were no significant differences between the patients with the classic CD group, and the nonclassic CD group, and the silent CD group (p = 0.564).

conclusionsThe study revealed that the median diagnostic delay was 7.30 months. Furthermore there were no significant differences between clinical subtypes of CD. In order to minimize the delay in diagnosis, it may be a solution to raise community-based awareness of CD, and better inform pediatricians, and family physicians about CD.

Indexed as

Celiac DiseaseDelayed DiagnosisAdolescentChildChild, PreschoolFemaleHumansMaleProspective StudiesSurveys and QuestionnairesTreatment DelayTurkeyCeliac diseaseChildrenDiagnostic delay

Identifiers

PMID41572164
PMCPMC12910729

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.