Evidence map›Paper›PMID 41572183›Full record

ArticleBMC neurology2026

Multiparameters of heart rate variability predict symptomatic hemorrhagic transformation in patients following mechanical thrombectomy.

Yuyang Lin, Yingwen Su, Shanglin Yang, Yi Liu, Xiaoqing Ouyang, Zhihua Xiao, Yunqing Chen, Zubing Xu, Xuwei Liao, Hongbin Zhou and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Yuyang Lin *Department of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China.
Yingwen Su *Department of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China.
Shanglin YangSchool of Electrical and Information Engineering, North Minzu University, Yinchuan, Ningxia, 750021, China.
Yi LiuDepartment of Neurology, Qingyuan District People's Hospital, Jian, Jiangxi, 343009, China.
Xiaoqing OuyangDepartment of Neurology, Qingyuan District People's Hospital, Jian, Jiangxi, 343009, China.
Zhihua XiaoDepartment of Neurology, Qingyuan District People's Hospital, Jian, Jiangxi, 343009, China.
Yunqing ChenDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China.
Zubing XuDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China.
Xuwei LiaoSchool of Electrical and Information Engineering, North Minzu University, Yinchuan, Ningxia, 750021, China.
Hongbin ZhouSchool of Electrical and Information Engineering, North Minzu University, Yinchuan, Ningxia, 750021, China.
Qin HuangDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China.
Jingwei HuangDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China.
Pu FangDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China.
Daojun HongDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China.
Jing LinDepartment of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330000, China. ndyfy08200@ncu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemorrhagic transformation (HT), especially symptomatic HT (sHT), seriously affects the functional prognosis in patients following mechanical thrombectomy (MT). The present study aimed to investigate the association of HT with heart rate variability (HRV) using multiple parameters in patients undergoing MT.

methodsBetween November 2019 and April 2024, we enrolled eligible patients according to the inclusion criteria and exclusion criteria. Linear parameters and nonlinear approaches reflecting HRV were calculated and analyzed.

resultsA total of 254 patients were included in the analysis, including 56 patients with HT and 198 patients without, and 24 patients with sHT and 230 patients without. Nonlinear approaches including SD1/SD2 ratio, Higuchi fractal dimension (HFD), large-scale multiscale entropy index (MSELS), multiscale entropy area under the curve (MSEAUC), large-scale composite multiscale entropy index (CMSELS), and composite multiscale entropy area under the curve (CMSEAUC) were showed to be independently associated with sHT (p < 0.05). Meanwhile, receiver operating characteristic curves suggested that CMSELS was a better indicator to predict sHT than other HRV parameters, with the area under the curve of 0.708 (95%CI 0.581–0.835).

conclusionsNonlinear parameters of HRV including SD1/SD2 ratio, HFD, MSELS, MSEAUC, CMSELS, and CMSEAUC provide an independent indicator for predicting sHT in patients following MT.

Indexed as

Cerebral HemorrhageHeart RateThrombectomyAgedFemaleHumansMaleMiddle AgedHeart rate variabilityHemorrhagic transformationLinear parametersMechanical thrombectomyNonlinear parameters

Identifiers

PMID41572183
PMCPMC12911255

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.