Evidence map›Paper›PMID 41572995›Full record

ArticleInternational journal of ophthalmology2026

Chronic alcohol consumption on retinal microcirculation in healthy subjects: an optic coherence tomography angiography study.

Dilan Yildiz, Tahsin Uzundede, Akin Cakir, Gamze Karatas, Busra Coban

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Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Dilan YildizDepartment of Ophthalmology, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul 34384, Türkiye.
Tahsin UzundedeDepartment of Ophthalmology, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul 34384, Türkiye.
Akin CakirDepartment of Ophthalmology, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul 34384, Türkiye.
Gamze KaratasDepartment of Ophthalmology, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul 34384, Türkiye.
Busra CobanDepartment of Ophthalmology, Viransehir Public Hospital, Sanliurfa 63700, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effects of chronic alcohol consumption on retinal microcirculation by comparing different alcohol-consuming groups using optical coherence tomography (OCT) and OCT angiography (OCTA).

methodsThis observational clinical study utilized a cross-sectional and prospective design, focusing on chronic alcohol consumers alongside a non-consuming control group. OCT/OCTA imaging parameters including central retinal subfield thickness (CST), subfoveal choroidal thickness (SCT), foveal avascular zone (FAZ) and vessel density (VD) in the superficial and deep capillary plexuses in both the macular and optic disc (OD) regions were recorded. Data were analyzed using SPSS 15.0; descriptive statistics were reported, group comparisons were performed with Chi-square, Kruskal-Wallis, and Bonferroni-corrected Mann-Whitney

resultsA total of 160 eyes of 160 participants (110 females and 50 males with mean age 38.7±9.9y) who don't smoke were divided into five groups: never, occasional, monthly, weekly and daily drinkers. The mean CST was 216.6±14.2 µm and the mean SCT was 358.9±84.5 µm. There was no statistically significantly difference in CST and SCT among the groups (

conclusionBoth superficial and deep microvascular structures in the inferior quadrants of macula are positively correlated with frequency of alcohol use. Also in our study results is that the monthly drinker group has uniquely higher VDs in both macula and OD. This leads us to consider moderate alcohol consumption may also have protective effects on retinal microcirculation.

Indexed as

alcohol consumptionfoveal avascular zoneoptical coherence tomography angiographyretinal microcirculationvessel density

Identifiers

PMID41572995
PMCPMC12820616

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.