Evidence map›Paper›PMID 41573565›Full record

ReviewFrontiers in immunology2025

Therapeutic antibody delivery: vector tools to boost efficacy and affordability.

Abhishek Chiyyeadu, Bushra Khan, Katrin Ehrhardt, Hildegard Büning, Michael Morgan, Axel Schambach

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abhishek ChiyyeaduInstitute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
Bushra KhanInstitute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
Katrin EhrhardtInstitute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
Hildegard BüningInstitute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
Michael MorganInstitute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
Axel SchambachInstitute of Experimental Hematology, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody (Ab)-based therapeutics have become powerful tools across diverse disease areas, with advances in bioengineering giving rise to next-generation molecules designed to outperform conventional Abs. Yet, large-scale production and purification of such complex proteins remain costly and can restrict patient access. A promising alternative is to improve

Indexed as

COVID-19Genetic VectorsGene Transfer TechniquesSARS-CoV-2AnimalsDependovirusGenetic TherapyHumansLentivirusAAV vectorsantibody deliveryinfectious diseaseslentiviral vectorsmRNA-LNPplasma cell therapy

Identifiers

PMID41573565
PMCPMC12819638

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.