ArticlebioRxiv : the preprint server for biology2026
Electrodiffusion active pump model with asymmetric immersed chemical potentials.
Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Electrodiffusion is essential in understanding the mechanisms of electrophysiology. Active exchange pumps are critical regarding volume homeostasis, and are also significant in the mechanisms of cell division, growth, and apoptosis. In the formalism of the immersed boundary (IB) method, we replace classical interface conditions across the membrane with regularized chemical potentials to control the permeation of each ionic species governed by the Poisson-Nernst-Planck equation. In asymmetry, to regulate ionic transport, continuous chemical potential barriers are augmented with energetic gradients represented by smoothed Heaviside kernels specifying the directions of active pumps. We obtain steadystate concentrations from electrodiffusion active pumps using Na
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