Evidence map›Paper›PMID 41574496›Full record

ReviewPediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society

EWSR1 Fusion Driven Pediatric B-Acute Lymphoblastic Leukemia: Diagnosis and Review of Literature.

Molly Talman, Ashwani K Yenamandra, Yassmine Akkari, Karen Tsuchiya, Scott C Borinstein, Nicolas Lopez-Hisijos, Brianna N Smith

Abstract readCase ReportsReview
In one paragraph

Review in Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Molly TalmanDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-8505-8329
Ashwani K YenamandraDepartment of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Yassmine AkkariThe Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Karen TsuchiyaThe Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA.ORCID 0000-0003-1406-5000
Scott C BorinsteinDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-1721-1520
Nicolas Lopez-HisijosDepartment of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Brianna N SmithDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

B-lymphoblastic leukemia/lymphoma (B-ALL) is the most prevalent childhood malignancy, with improved survival rates attributed to advances in diagnosis and treatment. Herein, we present a case of B-ALL in a 6-year-old female who presented with clinical symptoms of leukemia, including weight loss, fever, and lymphadenopathy. Molecular and cytogenetics study revealed a t(1;22) resulting in an

Indexed as

Oncogene Proteins, FusionPrecursor B-Cell Lymphoblastic Leukemia-LymphomaRNA-Binding Protein EWSChildFemaleHumansTranslocation, GeneticEWSR1 protein, humanOncogene Proteins, FusionRNA-Binding Protein EWSB-lymphoblastic leukemia/lymphoma (B-ALL)cytogeneticsEWSR1::PBX1 fusionRNA sequencing

Identifiers

PMID41574496
PMCPMC13084751

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.