Evidence map›Paper›PMID 41575217›Full record

ArticlemBio2026

Captivity drives multi-generational shifts in the gut microbiome that mirror changing animal fitness.

Candace L Williams, Claire E Williams, Shauna N D King, Debra M Shier

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Candace L Williams *Conservation Science, San Diego Zoo Wildlife Alliance, Escondido, California, USA.ORCID 0000-0002-1711-1183
Claire E Williams *University of Nevada, Reno, Nevada, USA.ORCID 0000-0002-8970-0032
Shauna N D KingConservation Science, San Diego Zoo Wildlife Alliance, Escondido, California, USA.
Debra M ShierConservation Science, San Diego Zoo Wildlife Alliance, Escondido, California, USA.ORCID 0000-0003-0262-6501

Funding

California Department of Fish and Wildlife Traditional Section 6U.S. Fish and Wildlife Service N62473-20-2-0016
6 · The paper itself

Abstract

Gut microbiomes can dramatically affect host health and fitness, but can shift rapidly under changing environmental conditions. Understanding the interplay between microbiota, environmental pressures, and host responses is critical for predicting species' resilience, particularly in populations transitioning from the wild to human care for conservation breeding. Although captivity can profoundly alter microbial communities and host physiology, the dynamics of these transitions across generations remain poorly understood. We evaluated gut microbiota and fitness metrics in the endangered Pacific pocket mouse (

Indexed as

Gastrointestinal MicrobiomeGenetic FitnessAnimalsBacteriaFemaleHost Microbial InteractionsMalecaptive breedinggut microbiomehost–microbiome interactionsmulti-generational samplingwildlife conservation

Identifiers

PMID41575217
PMCPMC12892941

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.