Evidence map›Paper›PMID 41575600›Full record

ArticleInflammation2026

Vascular Non-Inflammatory Molecule-1 Aggravates Acute Kidney Injury Induced Acute Lung Injury Via Promoting Neutrophil Extracellular Traps Formation.

Chang Liu, Yan Yang, Yi Song, Wenjun Wu, Peiling He, Yu Han, Wei Gu, Yijie Hu

Abstract read
In one paragraph

Article in Inflammation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chang Liu *Department of Cardiovascular Surgery, Daping Hospital, Army Medical University, No. 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, China.
Yan Yang *Department of Cardiovascular Surgery, Daping Hospital, Army Medical University, No. 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, China.
Yi Song *Department of Cardiovascular Surgery, Daping Hospital, Army Medical University, No. 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, China.
Wenjun WuDepartment of Cardiovascular Surgery, Daping Hospital, Army Medical University, No. 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, China.
Peiling HeDepartment of Cardiovascular Surgery, Daping Hospital, Army Medical University, No. 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, China.
Yu HanChongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Yuzhong District, Chongqing, 400042, China.
Wei GuSchool of Medicine, Chongqing University, No. 131 Yubei Road, Shapingba District, Chongqing, 400044, China. guwei@cqu.edu.cn.
Yijie HuDepartment of Cardiovascular Surgery, Daping Hospital, Army Medical University, No. 10 Changjiang Branch Road, Yuzhong District, Chongqing, 400042, China. yijie.hu@tmmu.edu.cn.

Funding

Joint project of Chongqing Health Commission and Science and Technology Bureau 2018ZDXM003National Natural Science Foundation of China No. 82372549
6 · The paper itself

Abstract

Acute kidney injury-induced acute lung injury (AKI-ALI) is a severe clinical syndrome characterized by systemic inflammation, oxidative stress, and immune cell activation. Vascular non-inflammatory molecule-1 (Vanin-1, VNN1), a pantetheinase enzyme involved in oxidative stress and inflammation, has been implicated in various inflammatory diseases. However, its role in AKI-ALI and its therapeutic potential remain unclear. An AKI-ALI model was established via bilateral kidney ischemia-reperfusion (KIR) in mice. VNN1

Indexed as

Acute Kidney InjuryAcute Lung InjuryAmidohydrolasesExtracellular TrapsNeutrophilsAnimalsGPI-Linked ProteinsMaleMiceMice, Inbred C57BLMice, KnockoutOxidative StressAmidohydrolasesGPI-Linked ProteinspantetheinaseAcute kidney injuryAcute lung injuryInflammationNeutrophil extracellular traps (NETs)Oxidative stressVanin-1 (VNN1)

Identifiers

PMID41575600
PMCPMC12886252

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.