Evidence map›Paper›PMID 41575695›Full record

ArticleDiscover oncology2026

Assessment circulating micro-RNA-192 in Egyptian patients with non-viral liver cirrhosis and hepatocellular carcinoma.

Mohamed Abdelaleim Abdelaziz, Abdallah Mohammed Elagali, Ayman S Soliman, Hader I Sakr, Ahmed A Ibrahim, Alaa H Huzien, Jakleen Z Abujamai, Ahmed A Damanhory, Safy S Gaber

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Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohamed Abdelaleim AbdelazizDepartment of Basic Medical Sciences, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
Abdallah Mohammed ElagaliDepartment of Histology, General Medicine Practice Program, Batterjee Medical College, Jeddah, 21442, Saudi Arabia.
Ayman S SolimanDepartment of Medical Physiology, Faculty of Medicine, Beni- Suef University, Beni Suef, Egypt.
Hader I SakrDepartment of Medical Physiology, Faculty of Medicine, Cairo University, Cairo, Egypt. hadersakr@kasralainy.edu.eg.ORCID https://orcid.org/0000-0003-2917-2423
Ahmed A IbrahimDepartment of Internal Medicine, Faculty of Medicine, Beni- Suef University, Beni Suef, Egypt.
Alaa H HuzienDepartment of Medical Physiology, Faculty of Medicine, Al Nahda University, New Bani Suef, Egypt.
Jakleen Z AbujamaiGeneral Medicine Practice Program, Batterjee Medical College, Jeddah, 21442, Saudi Arabia.
Ahmed A DamanhoryDepartment of Biochemistry, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Safy S GaberDepartment of Medical Physiology, Faculty of Medicine, Beni- Suef University, Beni Suef, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is challenging to diagnose hepatic cirrhosis and hepatocellular carcinoma (HCC) at an early stage since non-invasive markers are not specific and do not identify the early stage.

objectiveSerum microRNA-192 could represent an early and critical pathogenetic factor in different liver diseases.

methods92 participants were allocated into four equal groups (n = 23): control, compensated liver cirrhosis, decompensated cirrhosis, and HCC groups.

resultsDecompensated cirrhosis and HCC showed significantly elevated Serum Alanine aminotransferase, aspartate aminotransferase, bilirubin, alpha-fetoprotein, and microRNA-192.

conclusionSerum microRNA-192 can predict decompensated liver cirrhosis and HCC with high sensitivity and specificity.

Indexed as

Alpha fetoproteinAnd microRNA‑192Hepatic cirrhosisHepatocellular carcinoma

Identifiers

PMID41575695
PMCPMC12834849

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.