ArticleBMC public health2026
Trends in renal failure-related mortality among adults in the United States: a national cross-sectional analysis (CDC database study 1999-2023).
Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Demographic and regional disparities in concurrent respiratory and renal failure mortality: a CDC WONDER analysis, 1999-2024.Scientific reports · 2026Article
- Trends, underlying-cause structure, and penetration of end-stage kidney disease involvement in U.S. mortality, 1999-2023: a multiple-cause-of-death analysis.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Renal failure (RF) remains a major contributor to mortality in the United States, but how RF-related deaths have changed over time—and how those patterns differ across demographic and geographic groups—has not been well characterized. We used CDC WONDER multiple-cause-of-death data to examine RF-related mortality among U.S. adults aged ≥ 25 years from 1999 to 2023, defining RF as the underlying cause of death (ICD-10 N17–N19). We calculated age-adjusted mortality rates (AAMRs) per 100,000 and assessed temporal trends using joinpoint-derived average annual percent change (AAPC), overall and stratified by sex, age, race/ethnicity, U.S. census region, and urbanization. From 1999 to 2023, there were 1,138,750 RF-related deaths. Trends differed by region: the South consistently carried the highest burden and experienced the fastest increase in AAMR (AAPC = + 0.7605), whereas the Northeast showed a sustained decline (AAPC = − 0.5704). AAMRs were higher in females than in males throughout the study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.