Evidence map›Paper›PMID 41579273›Full record

ArticleMolecular biology reports2026

Hydrogen treatment attenuates ferroptosis and alleviates spinal cord ischemia-reperfusion injury by activating the Nrf2/HO-1 signaling pathway.

Jian Tong, Jie Liu, Zhengming Lv

Abstract read
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In one paragraph

Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jian TongDepartment of Orthopaedics, Taizhou School of Clinical Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Nanjing Medical University, 366 TaiHu Road, Taizhou, Jiangsu, China. tongjian0927@163.com.
Jie LiuDepartment of Orthopaedics, Taizhou School of Clinical Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Nanjing Medical University, 366 TaiHu Road, Taizhou, Jiangsu, China.
Zhengming LvDepartment of Orthopaedics, Taizhou School of Clinical Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Nanjing Medical University, 366 TaiHu Road, Taizhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSpinal cord ischemia-reperfusion injury (SCIRI) can lead to significant losses in sensory and motor functions. The precise role of hydrogen (H MATERIALS AND

methodsThis study used an abdominal aorta ligation technique to establish a SCIRI model in rats. Following oxygen-glucose deprivation/reoxygenation (OGD/R), HT22 cells were treated with H

resultsThe administration of H

conclusionsIn summary, these findings demonstrate that H

Indexed as

FerroptosisHeme Oxygenase-1HydrogenNF-E2-Related Factor 2Reperfusion InjurySpinal Cord IschemiaAnimalsDisease Models, AnimalHeme Oxygenase (Decyclizing)MaleMembrane Potential, MitochondrialOxidative StressRatsRats, Sprague-DawleyReactive Oxygen SpeciesSignal TransductionHeme Oxygenase-1Heme Oxygenase (Decyclizing)Hmox1 protein, ratHydrogenNfe2l2 protein, ratNF-E2-Related Factor 2Reactive Oxygen SpeciesFerroptosisHydrogenNrf2/HO-1 signaling pathwayRatsSpinal cord ischemia-reperfusion injury

Identifiers

PMID41579273

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.