Evidence map›Paper›PMID 41579355›Full record

ArticlePhysiological genomics2026

Monitored food intake in early pregnancy modulates the maternal microbiome in the obese BPH/5 mouse model of superimposed preeclampsia.

Kelly Fan, Chin-Chi Liu, Kalie F Beckers, Christopher J Schulz, Gary W Childers, Jenny L Sones

Abstract read
In one paragraph

Article in Physiological genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelly FanBaton Rouge Magnet High School, Baton Rouge, Louisiana, United States.
Chin-Chi LiuOffice of Research and Graduate Education, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana, United States.ORCID 0000-0003-0723-8313
Kalie F BeckersDivision of Veterinary Medicine, Tulane National Primate Research Center, Tulane University, Covington, Louisiana, United States.
Christopher J SchulzDepartment of Biological Sciences, Southeastern Louisiana University, Hammond, Louisiana, United States.
Gary W ChildersDepartment of Biological Sciences, Southeastern Louisiana University, Hammond, Louisiana, United States.
Jenny L SonesDepartment of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States.ORCID 0000-0002-5360-1243

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Lifecycle of obesogenic gender behaviors and cardiometabolic disease in womenR01HL165467 · NHLBI · COLORADO STATE UNIVERSITY · PI Jennifer Liford Sones · 2024 to 2026
$1.1M
HHS | National Institutes of Health (NIH) 1R01HL165467-01A1NHLBI NIH HHS R01 HL165467NIH HHS P51 OD011104
6 · The paper itself

Abstract

Preeclampsia (PE) is a life-threatening pregnancy disorder strongly associated with maternal obesity, yet the mechanistic links between diet, microbiome, and disease risk remain unclear. The obese BPH/5 mouse, which spontaneously develops PE-like features, provides a model to investigate how maternal nutrition influences microbial and metabolic profiles. Here, we tested the effects of modest caloric restriction [pair-fed (PF)] initiated at

Indexed as

EatingMicrobiotaObesityPre-EclampsiaAnimalsCaloric RestrictionDisease Models, AnimalFatty Acids, VolatileFecesFemaleMiceMice, ObesePregnancyRNA, Ribosomal, 16SFatty Acids, VolatileRNA, Ribosomal, 16Scaloric restrictionearly pregnancymaternal microbiomeobesitypreeclampsia

Identifiers

PMID41579355
PMCPMC13078920

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.