Evidence map›Paper›PMID 41580775›Full record

Trial reportBMC health services research2026

Enabling and hindering aspects of the i²TransHealth e-health intervention for transgender and gender diverse people in Germany: a qualitative process evaluation.

Franziska Schmidt, Janis Renner, Samantha-Insine Schröder, Lea Pregartbauer, Arne Dekker, Timo O Nieder

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04290286 (Interdisciplinary, Internet-based Trans Health Care), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04290286 nacompletednot on this map

Interdisciplinary, Internet-based Trans Health Care (i2TransHealth): A Randomized Controlled Trial

TypeinterventionalSponsorUniversitätsklinikum Hamburg-EppendorfRan2020 to 2022Enrolled186ConditionsGender Dysphoria, Gender Identity Disorder, Transsexualism, Gender IdentityArmsi2TransHealth
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Franziska Schmidt *Institute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany. fra.schmidt@uke.de.ORCID http://orcid.org/0000-0002-4087-0049
Janis Renner *Institute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0003-1063-1626
Samantha-Insine SchröderInstitute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0009-0007-5115-0948
Lea PregartbauerInstitute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0002-6862-6304
Arne Dekker *Institute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0003-1549-2020
Timo O Nieder *Institute for Sex Research, Sexual Medicine and Forensic Psychiatry, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0003-3052-5169

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransgender and gender diverse (TGD) people in remote areas face structural barriers to accessing gender-affirming, interdisciplinary healthcare. These include limited specialised care, a shortage of TGD-informed healthcare professionals, long travel distances to urban care centres, and insufficient local crisis support. The i²TransHealth intervention addressed these gaps by offering video consultations, chat-based support, and a network of locally trained physicians (general practitioners, psychiatrists). This qualitative process evaluation identified enabling and hindering aspects to inform recommendations for improving and scaling i²TransHealth, and to support the implementation of e-health in other TGD-informed care contexts.

methodsi²TransHealth was evaluated as an e-health intervention in a randomised controlled trial involving 174 TGD adult participants (aged 18 and above) from northern Germany. As part of the intervention group, service users received video consultations and chat-based support provided by study therapists, along with outpatient care from general practitioners and psychiatrists as needed. To capture the experiences of those involved in delivering and receiving the intervention, four online focus groups were conducted with service users (n = 4), study therapists (n = 5), general practitioners (n = 6), and psychiatrists (n = 7). Data were collected using semi-structured interview guides and analysed according to Kuckartz's thematic text analysis.

resultsThe process evaluation identified enabling and hindering aspects influencing the implementation of i²TransHealth. Focus group participants reported improved access to TGD-informed healthcare through i²TransHealth, though this was challenged by factors such as time constraints, administrative burdens, and limited referral options for specialised care. They highlighted the flexibility and support of study therapists, as well as reduced distress and increased wellbeing of service users. While video consultations facilitated access, they were considered challenging for assessing non-verbal cues and treating highly distressed individuals. The e-health platform enabled easily accessible communication, yet usability issues, inconsistent engagement, and high workload for study therapists were noted.

conclusionsE-health interventions like i²TransHealth can enhance access to TGD-informed healthcare in remote areas, but require integration with in-person services for complex cases involving highly distressed individuals. Expanding training, strengthening networks, and refining digital tools are crucial for sustainability.

trial registrationThe trial was registered in ClinicalTrials.gov 28/02/2020 (NCT04290286).

Indexed as

TelemedicineTransgender PersonsAdultFemaleFocus GroupsGermanyHealth Services AccessibilityHumansMaleMiddle AgedQualitative ResearchYoung AdultBarriers to accessing healthcareDigital healthe-healthGender diverseImplementationProcess evaluationQualitative text analysisRCTRemote careTransgender

Identifiers

PMID41580775
PMCPMC12849576

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.