Evidence mapPaperPMID 41580950Full record

ReviewTherapeutic advances in cardiovascular disease

Troponins and echocardiography: role in detecting myocardial injury in burn patients.

Mohammed AbuBaha, Samia Aldwaik, Ameer Awashra, Fathi Milhem, Anwar Zahran, Husam Hamshary, Hasan Fuqha, Mohammad Bdair, Bara Abubaha, Sarah Saife and 1 more

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In one paragraph

Review in Therapeutic advances in cardiovascular disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohammed AbuBahaDepartment of Medicine, An-Najah National University, Nablus, Palestine.
Samia AldwaikDepartment of Medicine, An-Najah National University, Nablus P400, Palestine.ORCID 0009-0005-0866-7787
Ameer AwashraDepartment of Medicine, An-Najah National University, Nablus, Palestine.ORCID 0009-0002-5122-8200
Fathi MilhemDepartment of Medicine, An-Najah National University, Nablus, Palestine.
Anwar ZahranDepartment of Medicine, An-Najah National University, Nablus, Palestine.ORCID 0009-0001-7767-6573
Husam HamsharyDepartment of Medicine, An-Najah National University, Nablus, Palestine.
Hasan FuqhaDepartment of Medicine, An-Najah National University, Nablus, Palestine.
Mohammad BdairDepartment of Medicine, An-Najah National University, Nablus, Palestine.
Bara AbubahaDepartment of Medicine, An-Najah National University, Nablus, Palestine.
Sarah SaifeDepartment of Medicine, An-Najah National University, Nablus, Palestine.
Abdalhakim ShubietahDepartment of Medicine, An-Najah National University, Nablus, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe burn injuries result in a massive systemic inflammatory and hypermetabolic response, often disrupting multiple organ systems, including the cardiovascular system. Cardiac troponins are frequently elevated in burn patients, but the interpretation of these elevations is hardly straightforward. Sometimes, elevated troponin means type 1 myocardial infarction (MI) due to an acute coronary event, but it might also reflect type 2 MI due to an imbalance between body oxygen demand and supply, or even non-ischemic myocardial injury from things like overwhelming inflammation, sepsis, or direct thermal effects on the heart itself. This narrative review explores the prevalence, underlying pathophysiological mechanisms, diagnostic challenges, and prognostic implications of troponin elevation in burn patients. We discussed the limitations of applying conventional MI diagnostic criteria in this unique population. The role of electrocardiographic and echocardiographic assessment, as well as the potential utility of high-sensitivity troponin assays, is also discussed. Understanding of how burn pathophysiology relates to myocardial injury is essential for accurate diagnosis, improved management, and better outcomes in this highly vulnerable group of patients.

Indexed as

BurnsEchocardiographyMyocardial InfarctionTroponinBiomarkersElectrocardiographyHumansMyocardiumPredictive Value of TestsPrognosisBiomarkersTroponinburn cardiomyopathyburn injurycardiac dysfunctioncardiac troponinechocardiographyfluid resuscitationglobal longitudinal strainhigh-sensitivity troponinmyocardial injury

Identifiers

PMID41580950
PMCPMC12833205

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.