Evidence map›Paper›PMID 41580973›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells.

Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jin LiFaculty of Medicine, Dalian University of Technology, Dalian, Liaoning, China.
Hang ZhengDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), Shandong Key Laboratory of Druggability Optimization and Evaluation for Lead Compounds, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Yuxing LinInstitute of Medical Sciences, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Ziwei ZhaoDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), Shandong Key Laboratory of Druggability Optimization and Evaluation for Lead Compounds, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Yijia MaiDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), Shandong Key Laboratory of Druggability Optimization and Evaluation for Lead Compounds, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Zhangrong LouFaculty of Medicine, Dalian University of Technology, Dalian, Liaoning, China.
Qiang LiuFaculty of Medicine, Dalian University of Technology, Dalian, Liaoning, China.
Zhao MaDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), Shandong Key Laboratory of Druggability Optimization and Evaluation for Lead Compounds, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.ORCID https://orcid.org/0000-0002-8000-5324
Chengjun WuFaculty of Medicine, Dalian University of Technology, Dalian, Liaoning, China.

Funding

National Natural Science Foundation of China 82072287Natural Science Foundation of Shandong Province 2023HWYQ-033Natural Science Foundation of Shandong Province ZR2024MB095Taishan Scholar Project of Shandong Province tsqn202306027
6 · The paper itself

Abstract

Mitochondria, pivotal for cellular bioenergetics and signaling, are attractive targets for cancer therapy. Triphenylphosphonium (TPP

Indexed as

CardiolipinsMitochondriaNeoplasmsOrganophosphorus CompoundsAnimalsApoptosisCell Line, TumorHumansMembrane Potential, MitochondrialMiceMitochondrial MembranesCardiolipinsOrganophosphorus Compoundscancer cellscardiolipinmitochondriaoncosistriphenylphosphonium

Identifiers

PMID41580973
PMCPMC13042706

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.