Evidence map›Paper›PMID 41580986›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Dorsal Raphe VIP Neurons Are Critical for Survival-Oriented Vigilance.

Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze and 6 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Adriane GuillauminUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0002-6488-3207
Emma PerrotUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0009-0000-5044-9795
Thibault DhellemmesUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0009-0004-2325-8386
Laura BoiDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-5345-8478
Daniel De Castro MedeirosDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-0243-1309
Christelle GlangetasUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0001-9544-4277
Sylvie DumasORAMACELL, Paris, France.
Sandra DoveroUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0002-5781-1328
Nathalie BiendonUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0002-5180-5656
Elodie LadevezeUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0003-2506-6834
Maëlle HardelUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0009-0003-3000-6761
Marc LandryUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0003-3936-324X
Erwan BezardUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0002-0410-4638
Jérôme BaufretonUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0002-2623-6375
Gilberto FisoneDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-0719-8000
François GeorgesUniv. Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.ORCID https://orcid.org/0000-0002-2628-2638

Funding

European Union's Horizon 2020 research and innovation program under grant agreement 848002French government in the framework of the University of Bordeaux's IdEx "Investments for the Future" program GPR BRAIN_2030H2020 European Institute of Innovation and Technology AND-PD
6 · The paper itself

Abstract

Defensive behaviors are essential for survival, relying on risk assessment to detect and respond to threats. The dorsal raphe nucleus (DRN), a brain region involved in sleep-wake regulation, contains dopaminergic neurons (DRN

Indexed as

Dopaminergic NeuronsDorsal Raphe NucleusNeuronsVasoactive Intestinal PeptideAnimalsMaleMiceMice, Inbred C57BLSeptal NucleiSleepWakefulnessVasoactive Intestinal Peptideamygdalaanxietybed nucleus of the stria terminaliscentral extended amygdaladefensive behaviordopaminergic neurons heterogeneityescapeNREM sleeprisk assessmentvasoactive intestinal peptide

Identifiers

PMID41580986
PMCPMC13042892

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.