Evidence map›Paper›PMID 41582147›Full record

ArticleBMC nutrition2026

The association of dietary approach to stop hypertension (DASH) with risk of gallstone disease: a case control study.

Zahra Dianati, Nazanin Shahrokhnia, Azita Hekmatdoost, Moloud Ghorbani, Amir Sadeghi, Zahra Yari

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Article in BMC nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Zahra DianatiClinical Nutrition and Dietetics Department, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nazanin ShahrokhniaSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Azita HekmatdoostClinical Nutrition and Dietetics Department, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Moloud GhorbaniDepartment of Nutrition, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir SadeghiResearch Institute for Gastroenterology and Liver Diseases of Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zahra YariDepartment of Nutrition Research, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, West Arghavan St. Farahzadi Blvd., Sharake Qods, Tehran, Iran. zahrayari_nut@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimSince little is known about the association between diet and gallstone disease (GSD), in this study, we investigated the relationship between Dietary Approaches to Stop Hypertension (DASH) and the risk of GSD.

methodsIn this case–control study, 189 patients with newly diagnosed GSD and 342 healthy controls were included. The DASH score was calculated using a 168-item semi-quantitative validated food frequency questionnaire. Participants were classified into tertiles based on the DASH diet score. Crude and multivariable logistic regression models were applied to estimate the odds ratio (OR) and 95% confidence interval (CI) for risk of GSD across tertiles of DASH score.

resultsThe mean ± standard deviation of DASH score in patients with GSD and controls was 22.6 ± 4.2 and 24.9 ± 4.9, respectively (P < 0.001). The risk of GSD in the highest tertile of DASH score was 82% lower than the lowest tertile (OR = 0.18, 95%CI: 0.1–0.3, P < 0.001) after full adjustment for confounders. In addition, higher intake of vegetables, legumes, nuts and seeds, whole grains, and low-fat dairy products were significantly associated with a reduced risk of GSD (P trend < 0.001). In contrast, red and processed meats (P trend = 0.034), sweetened beverages (P trend = 0.019), and sodium (P trend = 0.050) were significantly associated with an increased risk of GSD.

conclusionsThese findings provide evidence that adherence to the DASH is associated with a lower risk of GSD. Further investigations are required to confirm our findings.

Indexed as

CholelithiasisDASH dietDietary patternGallstone

Identifiers

PMID41582147
PMCPMC12914998

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