Evidence map›Paper›PMID 41582154›Full record

ArticleNature communications2026

The network architecture of general intelligence in the human connectome.

Ramsey R Wilcox, Babak Hemmatian, Lav R Varshney, Aron K Barbey

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Giftedness: A Critical Analysis of Theories and Identification Methods in Light of Contemporary Neuroscience.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ramsey R WilcoxDecision Neuroscience Laboratory, University of Notre Dame, Notre Dame, IN, USA.
Babak HemmatianAI Innovation Institute, Stony Brook University, Stony Brook, NY, USA.
Lav R VarshneyAI Innovation Institute, Stony Brook University, Stony Brook, NY, USA.
Aron K BarbeyDecision Neuroscience Laboratory, University of Notre Dame, Notre Dame, IN, USA. abarbey@nd.edu.ORCID 0000-0002-6092-0912

Funding

ODNI | Intelligence Advanced Research Projects Activity (IARPA) 2014-13121700004United States Department of Defense | Defense Advanced Research Projects Agency (DARPA) 2019-HR00111990067
6 · The paper itself

Abstract

Advances in network neuroscience challenge the view that general intelligence (g) emerges from a primary brain region or network. Network Neuroscience Theory (NNT) proposes that g arises from coordinated activity across the brain's global network architecture. We tested predictions from NNT in 831 healthy young adults from the Human Connectome Project. We jointly modeled the brain's structural topology and intrinsic functional covariation patterns to capture its global topological organization. Our investigation provided evidence that g (1) engages multiple networks, supporting the principle of distributed processing; (2) relies on weak, long-range connections, emphasizing an efficient and globally coordinated network; (3) recruits regions that orchestrate network interactions, supporting the role of modal control in driving global activity; and (4) depends on a small-world architecture for system-wide communication. These results support a shift in perspective from prevailing localist models to a theory that grounds intelligence in the global topology of the human connectome.

Indexed as

BrainConnectomeIntelligenceNerve NetAdultFemaleHumansMagnetic Resonance ImagingMaleModels, NeurologicalYoung Adult

Identifiers

PMID41582154
PMCPMC12946243

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.