Evidence map›Paper›PMID 41583530›Full record

ArticleInternational journal of medical sciences2026

Effects of NGR1 on the Protective Efficacy and Functional Vision Profile of Retinal Photodamage.

Chi-Huang Chang, Jyh-Cheng Liou, Yi-Hsien Hsieh, Shih-Liang Yang, Chi-Wu Chang, Shao-Yun Tsai, Jui-Yi Yu, Ling Lu, Ping-Hsun Wang, Bo-Yie Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chi-Huang ChangDepartment of Ophthalmology, Chung Shan Medical University Hospital, Taichung City 40201, Taiwan, ROC.
Jyh-Cheng LiouDepartment of Ophthalmology, Chung Shan Medical University Hospital, Taichung City 40201, Taiwan, ROC.
Yi-Hsien HsiehInstitute of Medicine, Chung Shan Medical University, Taichung City 40201, Taiwan, ROC.
Shih-Liang YangDepartment of Chinese Medicine, Taichung Hospital, Ministry of Health and Welfare, Taichung City 40343, Taiwan, ROC.
Chi-Wu ChangDepartment of Ophthalmology, Chung Shan Medical University Hospital, Taichung City 40201, Taiwan, ROC.
Shao-Yun TsaiDepartment of Optometry, Chung Shan Medical University, Taichung City 40201, Taiwan, ROC.
Jui-Yi YuDepartment of Optometry, Chung Shan Medical University, Taichung City 40201, Taiwan, ROC.
Ling LuDepartment of Optometry, Chung Shan Medical University, Taichung City 40201, Taiwan, ROC.
Ping-Hsun WangDepartment of Ophthalmology, Chung Shan Medical University Hospital, Taichung City 40201, Taiwan, ROC.
Bo-Yie ChenDepartment of Ophthalmology, Chung Shan Medical University Hospital, Taichung City 40201, Taiwan, ROC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged exposure to high-intensity light can harm macula vision, particularly affecting the function of Müller cells and cone photoreceptors. Panax notoginseng saponins (PNS) have valuable pharmacological effects on cerebrovascular, neurological, and microcirculatory health. Notoginsenoside R1 (NGR1), derived from PNS, shows potential for treating vascular or ischemia-reperfusion-related retinal issues; however, its impact on cone cells and the functional vision profile is not well understood. This study aimed to explore the effect and efficacy of NGR1 on retinal photodamage

Indexed as

GinsenosidesRetinaAnimalsDisease Models, AnimalElectroretinographyEpendymoglial CellsHumansLightMaleMiceRetinal Cone Photoreceptor CellsVision, OcularVisual AcuityGinsenosidesnotoginsenoside R1cone opsinNotoginsenoside R1photoreceptorvisual acuityvisual contrast sensitivity function

Identifiers

PMID41583530
PMCPMC12825012

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.