Evidence mapPaperPMID 41584074Full record

ArticleFrontiers in dental medicine2025

IL-6, calcium, salivary amylase activity and cortisol as a salivary biomarker-combination associated with obesity: a pilot study.

H Al Habobe, E B Haverkort, K Nazmi, L K Van Nieukerken, V E A Gerdes, F J Bikker, R H H Pieters

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Article in Frontiers in dental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

H Al HabobeResearch Group Innovative Testing in Life Sciences and Chemistry, Research Centre for Healthy and Sustainable Living, University of Applied Sciences Utrecht, Utrecht, Netherlands.
E B HaverkortResearch Group Innovations in Preventive Care, University of Applied Sciences Utrecht, Utrecht, Netherlands.
K NazmiDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, Netherlands.
L K Van NieukerkenDepartment of Bariatric Surgery, Spaarne Gasthuis Hospital, Hoofddorp, Netherlands.
V E A GerdesDepartment of Bariatric Surgery, Spaarne Gasthuis Hospital, Hoofddorp, Netherlands.
F J BikkerDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, Netherlands.
R H H PietersResearch Group Innovative Testing in Life Sciences and Chemistry, Research Centre for Healthy and Sustainable Living, University of Applied Sciences Utrecht, Utrecht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: As obesity continues to escalate to pandemic levels worldwide, innovative approaches for early diagnosis, risk stratification, and disease monitoring are urgently needed. Saliva presents a promising non-invasive method for biomarker-based screening in obesity. Objective: This study aimed to utilize a multi-biomarker approach to explore associations between salivary biomarkers and obesity. This was done by measuring a pre-selected panel of obesity-related salivary biomarkers and comparing their levels between individuals with and without obesity. Methods: Unstimulated saliva was collected from 57 individuals, including 27 individuals diagnosed with obesity (BMI ≥ 30 kg/m Results: The results indicated lower Ca Conclusions: In conclusion, this study highlights IL-6, Ca

Indexed as

calciumcortisolIL-6obesitysAAsaliva

Identifiers

PMID41584074
PMCPMC12827711

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.