Evidence map›Paper›PMID 41584179›Full record

ReviewFrontiers in public health2025

AI-driven transformation of precision medicine: a comprehensive narrative review of key application areas, emerging paradigms, and future directions.

Qin Zeng, Cheng Huang, Jun Zhu

Abstract readReview
In one paragraph

Review in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qin ZengDepartment of Pediatric Gastroenterology Nursing, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Cheng HuangKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.
Jun ZhuKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aims to elucidate the pivotal role of Artificial Intelligence (AI) in driving the transformation of precision medicine, comprehensively analyzing how it reshapes healthcare systems from traditional diagnosis and treatment paradigms into personalized health management ecosystems. Methods: A comprehensive narrative review was conducted to systematically synthesize and critically evaluate the innovative applications, paradigm shifts, and future prospects of AI across the entire precision medicine value chain. A comprehensive literature search was performed across multiple databases up to April 30, 2025, with a focus on the clinical implementation and breakthroughs of technologies such as deep learning (DL), machine learning (ML), and natural language processing (NLP). Results: AI technologies have significantly enhanced the accuracy and efficiency of disease diagnosis through medical image analysis, genomics, and multimodal data fusion. At the treatment level, AI enables the development of personalized therapeutic plans and drug dosing optimization, while revolutionarily accelerating the drug development pipeline from discovery to clinical trials. Integrated with wearable devices and telemedicine platforms, AI facilitates full-cycle health monitoring. However, the clinical translation of AI faces challenges, including an uneven evidence base, insufficient model generalizability, and ethical concerns regarding data privacy, algorithmic fairness, and interpretability. Conclusion: AI is a key driver of paradigm shift in precision medicine. To address existing challenges, future efforts should focus on generating more robust clinical evidence, adopting technologies like federated learning to ensure data privacy, and promoting the human-centered, collaborative framework of Symbiotic AI (SAI). By establishing sound ethical and governance structures, the deployment of AI technologies can be ensured to be not only efficient and advanced but also equitable and trustworthy, ultimately paving the way for an intelligent and inclusive healthcare ecosystem.

Indexed as

Artificial IntelligencePrecision MedicineDeep LearningDigital HealthHumansMachine Learningartificial intelligencedeep learninghealthcare ethicspersonalized treatmentprecision medicineremote monitoringsymbiotic artificial intelligence

Identifiers

PMID41584179
PMCPMC12823851

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.