Evidence map›Paper›PMID 41584408›Full record

ArticleJournal of diabetes research2026

Clinical Significance of Conjunctival Microvascular Density in Diabetic Retinopathy: A Multimodal Correlation Study Based on Swept-Source Optical Coherence Tomography Angiography.

Xiaoli Huang, Jiajia Yu, Wenjun Zou, Xiaoli Xiang, Hu Liu

Abstract read
In one paragraph

Article in Journal of diabetes research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoli HuangDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing City, Jiangsu Province, China, njmu.edu.cn.ORCID https://orcid.org/0000-0001-7241-5297
Jiajia YuDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing City, Jiangsu Province, China, njmu.edu.cn.
Wenjun ZouDepartment of Ophthalmology, Jiangnan University Medical Center, Wuxi No.2 People's Hospital, Wuxi City, Jiangsu Province, China.
Xiaoli XiangDepartment of Ophthalmology, Affiliated Changshu Hospital of Nantong University, Changshu City, Jiangsu Province, China.ORCID https://orcid.org/0000-0001-7020-0962
Hu LiuDepartment of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing City, Jiangsu Province, China, njmu.edu.cn.ORCID https://orcid.org/0000-0002-5545-3926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy (DR) with media opacity presents a diagnostic challenge for retinal evaluation. This study investigated whether conjunctival microvascular assessment using swept-source optical coherence tomography angiography (SS-OCTA) can serve as a potential indicator of retinal pathology. We conducted a comparative study of 163 patients with diabetes (110 with DR, subdivided into 55 nonproliferative and 55 proliferative cases) and 49 age-matched healthy controls. All participants underwent SS-OCTA for conjunctival vessel density (VD) measurement and standard retinal OCTA for retinal VD and ganglion cell complex (GCC) analysis. Statistical correlations were performed to evaluate the relationship between the conjunctival and retinal parameters. Conjunctival VD showed a progressive reduction in DR severity, most prominently in the temporal region (70.7% in controls vs. 55.6% in patients with proliferative diabetic retinopathy [PDR]). Temporal conjunctival VD correlated well with retinal damage, and lower conjunctival density was linked to reduced retinal blood flow (

Indexed as

ConjunctivaDiabetic RetinopathyMicrovascular DensityMicrovesselsTomography, Optical CoherenceAdultAgedCase-Control StudiesFemaleFluorescein AngiographyHumansMaleMiddle AgedRetinal Vessels

Identifiers

PMID41584408
PMCPMC12831052

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.