Evidence map›Paper›PMID 41584591›Full record

ReviewFrontiers in oncology2025

Ferroptosis: a new dawn in the treatment of acute lymphoblastic leukemia.

Jiongping Han, Yifan Yang, Yuxin Wei, Jing Jin, Weiying Feng

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. The Emerging Role of Ferroptosis in Pediatric Cancer Biology and Therapy.International journal of molecular sciences · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiongping Han *Department of Hematology, Shaoxing People's Hospital, The First Hospital of Shaoxing University, Shaoxing, China.
Yifan Yang *Department of Hematology, Shaoxing People's Hospital, The First Hospital of Shaoxing University, Shaoxing, China.
Yuxin WeiDepartment of Hematology, Shaoxing People's Hospital, The First Hospital of Shaoxing University, Shaoxing, China.
Jing JinDepartment of Hematology, Shaoxing People's Hospital, The First Hospital of Shaoxing University, Shaoxing, China.
Weiying FengDepartment of Hematology, Shaoxing People's Hospital, The First Hospital of Shaoxing University, Shaoxing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lymphoblastic leukemia poses substantial challenges in therapeutic management. As a novel form of programmed cell death, ferroptosis has emerged as a promising research direction in cancer therapy. Studies have emphasized the pivotal role of ferroptosis in ALL, indicating that targeting this pathway could provide a novel therapeutic strategy. This article systematically reviews the molecular regulatory mechanisms of ferroptosis in ALL and explores its potential clinical applications in the treatment and prognostic evaluation of the disease.

Indexed as

acute lymphoblastic leukemiaferroptosisferroptosis-inducing drugsferroptosis-related genesmolecular mechanism

Identifiers

PMID41584591
PMCPMC12827144

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.