Evidence map›Paper›PMID 41584705›Full record

ArticleChinese herbal medicines2026

Genome-wide identification and characterization of methyltransferase involved in benzylisoquinoline alkaloids biosynthesis from

Yuwei Ma, Yaning Fu, Ge Bai, Shancen Zhao, Ya Tian, Ziyuan Zhao, Yan Wang, Zhichao Xu, Yong Chen, Zhoujie An and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chinese herbal medicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuwei MaBeijing Life Science Academy, Beijing 102209, China.
Yaning FuBeijing Life Science Academy, Beijing 102209, China.
Ge BaiBeijing Life Science Academy, Beijing 102209, China.
Shancen ZhaoBeijing Life Science Academy, Beijing 102209, China.
Ya TianKey Laboratory of National Forestry and Grassland Administration on Chinese Herbal Medicine, College of Life Science, Northeast Forestry University, Harbin 150040, China.
Ziyuan ZhaoShenyang Analytical Application Center, Shimadzu (China) Co., Ltd., Shenyang 110016, China.
Yan WangShenyang Analytical Application Center, Shimadzu (China) Co., Ltd., Shenyang 110016, China.
Zhichao XuKey Laboratory of National Forestry and Grassland Administration on Chinese Herbal Medicine, College of Life Science, Northeast Forestry University, Harbin 150040, China.
Yong ChenBeijing Life Science Academy, Beijing 102209, China.
Zhoujie AnKey Laboratory of National Forestry and Grassland Administration on Chinese Herbal Medicine, College of Life Science, Northeast Forestry University, Harbin 150040, China.
Ranran GaoArtemisinin Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Benzylisoquinoline alkaloids (BIAs) are valuable plant metabolites whose structural diversity largely depends on Methods: Combining genomic and biochemical approaches, a genome-wide identification of methyltransferase (MT) genes was conducted using the published Results: Functional characterization of the 75 methyltransferases identified in the Conclusion: This research elucidates the functional landscape of OMTs/NMTs in

Indexed as

benzylisoquinoline alkaloidsenzyme promiscuityMenispermum dauricum DCO-/N-methyltransferasessubstrate specificity

Identifiers

PMID41584705
PMCPMC12828156

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.