ReviewFrontiers in medicine2025
Application and development of stimulus-responsive hydrogel biomaterials for diabetic wound healing: a literature review.
Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Cell-derived vesicle-modified biomaterials for tissue repair and regeneration.Materials today. Bio · 2026Review
- Exosome-Biomaterial Platforms for Diabetic Skin Infections: Microenvironment Remodeling, Responsive Delivery, and Clinical Translation.International journal of nanomedicine · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
Diabetic wounds (DWs) are a severe complication of diabetes, defined as the presence of ulcers or deep tissue damage below the ankle in diabetic patients. DWs entail enormous psychological and economic burdens on diabetic patients. The microenvironment of diabetic wound healing is highly complex, characterized by hyperglycemia, excessive inflammation and elevated reactive oxygen species (ROS), making wound repair and healing extremely challenging. Traditional wound dressings have single function and insufficient adaptability to the wound environment, making it difficult to meet the complex needs of the healing process. As an emerging biomaterial, hydrogels offer distinct advantages over traditional dressings in terms of water absorption, breathability, biocompatibility, drug-carrying capacity, and environmental responsiveness, making them a subject of significant interest in the repair of diabetic wounds. Based on the diabetic wound microenvironment, we summarize and discuss hydrogel wound dressings responsive to temperature, pH, glucose, reactive oxygen species, enzymes, and multiple stimuli, integrating recent research advances in stimulus-responsive wound dressings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.