ArticleF1000Research2025
Glucose Tolerance Test (GTT) Curves of Water and Ethanol Extracts of Whole Body Apis mellifera jemenitica.
Article in F1000Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This article explored the chemical constituents of water and ethanol extracts from the whole body of Methods: Chemical analysis of the extracts was performed using infrared (IR) spectroscopy alongside the spectral database of organic compounds. Results: The water extract revealed a richer diversity of natural products (38 compounds) compared to the ethanol extract (12 compounds). Notably, the water extract comprised various bioactive molecules, including sugars and their derivatives, phenolic compounds, alkaloids, quinones, amino acid derivatives, dipeptides, and organometallic compounds. In contrast, the ethanol extract primarily contained sugar derivatives, phenolic compounds, alkaloids, and pesticides. The water extract decreased the blood glucose level and transformed the GTT curve from a convex to a concave shape. Conclusion: The blood glucose-lowering effect of the water extract may be attributed to the anti-diabetic properties of its dipeptides, phenolic compounds and alkaloid contents.
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