Evidence mapPaperPMID 41585473Full record

ArticleiScience2026

Interpretable machine learning for predicting low-dose methylprednisolone effectiveness in long COVID.

Jisheng Zhang, Yang Chen, Aijun Zhang, Yi Yang, Liqian Ma, Kewei Yu, Weitao Zhang, Xiaojing Ye, Jiangsong Zhang, Ke Lin and 1 more

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jisheng ZhangThe Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Yang ChenThe First Hospital of Jiaxing, Jiaxing, Zhejiang, China.
Aijun ZhangThe First Hospital of Jiaxing, Jiaxing, Zhejiang, China.
Yi YangHaining People's Hospital, Jiaxing, Zhejiang, China.
Liqian MaThe Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Kewei YuThe Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Weitao ZhangThe Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Xiaojing YeThe Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Jiangsong ZhangThe Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Ke LinThe First Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Xianming LinThe Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long COVID is a chronic, multisystem disease with limited response to conventional treatments. While low-dose methylprednisolone has shown effectiveness in some patients, individual responses vary, and accurate predictive tools are lacking. This retrospective study included 330 long COVID patients who received low-dose methylprednisolone treatment across three hospitals. Patients were divided into training (

Indexed as

Artificial intelligence applicationsTherapeutics

Identifiers

PMID41585473
PMCPMC12830216

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.