Evidence map›Paper›PMID 41585651›Full record

ReviewACS omega2026

Transforming Coagulation Testing: The Role of Biosensors in Prothrombin Time (PT) Measurement.

Induni Nayodhara Weerarathna, Praveen Kumar, Siah Kundy, Mayur Suresh Gawande, Matteo Hirushan Jayakody Arachchige, Sanvi Arora

Abstract readReview
In one paragraph

Review in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Induni Nayodhara WeerarathnaDepartment of Biomedical Sciences, Datta Meghe Institute of Higher Education and Research Deemed to be university, Wardha, Maharashtra-442107, India.ORCID https://orcid.org/0009-0007-6996-8270
Praveen KumarDepartment of Computer Science and Medical Engineering, Datta Meghe Institute of Higher Education and Research Deemed to be university, Wardha, Maharashtra-442107, India.
Siah KundyDepartment of Clinical Psycology, Datta Meghe Institute of Higher Education and Research, Deemed to be university, Wardha, Maharashtra-442107, India.
Mayur Suresh GawandeDepartment of Artificial Intelligence and Data Science, Datta Meghe Institute of Higher Education and Research Deemed to be university, Wardha, Maharashtra-442107, India.
Matteo Hirushan Jayakody ArachchigeDepartment of Microbiology and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Sanvi AroraDepartment of Medicine, Datta Meghe Institute of Higher Education and Research Deemed to be university, Wardha, Maharashtra-442107, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A key component of blood coagulation evaluation, prothrombin time (PT) measurement is used to diagnose clotting abnormalities, track anticoagulant treatments, and evaluate liver function. Despite their clinical significance, traditional PT testing techniques frequently depend on centralized laboratory setups, which can be costly, time-consuming, and unavailable to many patients. New developments in biosensor technology provide revolutionary ways to overcome these restrictions. This article discusses the cutting-edge field of biosensors for PT monitoring, going over fundamental ideas, current developments, and potential applications. In order to facilitate quick, precise, and least intrusive coagulation monitoring, biosensors have used technologies including microfluidics, nanotechnology, and bio-MEMS (Micro-Electro-Mechanical Systems). Their usefulness in point-of-care (PoC) and home-based settings has been further increased by developments in device portability and integration with digital health platforms, promoting individualized healthcare. Strategies to increase sensitivity, selectivity, and cost-effectiveness are highlighted in the design and construction of PT biosensors. This thorough analysis emphasizes how important biosensors are to advancing PT assessment and enhancing clinical results. Biosensor technologies have the potential to revolutionize the diagnostic landscape by providing adequate and affordable coagulation monitoring solutions in various healthcare settings with sustained research and interdisciplinary cooperation.

Identifiers

PMID41585651
PMCPMC12824724

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.