ArticleACS omega2026
3D Bioprinted Natural Hydrogels: Rheological Characterization, Cytotoxicity, and Printability Assessment of a Polysaccharide-Based Bioink.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Biomedical Hydrogels Based on Oxidized Hyaluronic Acid and Carboxymethyl Chitosan Coordinated with Magnesium Ions.Biomimetics (Basel, Switzerland) · 2026Article
- Anionic Polysaccharides: Promising 3D Bioink Candidates for Tissue Engineering.Bioengineering (Basel, Switzerland) · 2026Review
- Quantitative Assessment of Hydrogel Printability in Extrusion Bioprinting.Gels (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The creation of natural bioinks suitable for three-dimensional (3D) bioprinting remains a significant challenge in developing functional and biocompatible materials for tissue engineering. In this work, a novel bioink formulation was designed using food-grade polysaccharides, κ-carrageenan (KC), tragacanth gum (TG), and konjac glucomannan (KG), and thoroughly evaluated. Each component was tested at varying concentrations through rheological analysis, in vitro cytotoxicity assays (MTS test with HEK293T cells), and printability assessments using a commercial bioprinter. Optimal concentration ranges were identified as ≥2% for KC, ≥1.5% for TG, and 1.5-2% for KG, which were then combined into two candidate hydrogel formulations (A and B). Both exhibited viscoelastic behavior and pseudoplastic flow characteristics. Formulation B (2% KG) demonstrated greater structural rigidity (
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.