Evidence map›Paper›PMID 41586933›Full record

ArticleArchives of osteoporosis2026

Midlife physical activity, BMI, and hip fracture risk five decades later in men: a NOREPOS study.

Ida Kalstad Landgraff, Marius Myrstad, Anette Hylen Ranhoff, Ove Talsnes, Kristin Holvik, Haakon E Meyer

Abstract read
In one paragraph

Article in Archives of osteoporosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Secondary fracture risk after hip fracture in older patients: an updated sex-specific systematic review and meta analysis with GRADE and PAF assessment.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ida Kalstad LandgraffDepartment of Internal Medicine, Bœrum Hospital, Vestre Viken Hospital Trust, Gjettum, Norway. idwlan@vestreviken.no.ORCID 0000-0003-2238-4415
Marius MyrstadDepartment of Internal Medicine, Bœrum Hospital, Vestre Viken Hospital Trust, Gjettum, Norway.ORCID 0000-0002-9682-5255
Anette Hylen RanhoffDepartment of Internal Medicine, Diakonhjemmet Hospital, Oslo, Norway.ORCID 0000-0001-8690-4753
Ove TalsnesDepartment of Orthopedics, Innlandet Hospital Trust, Elverum, Norway.ORCID 0000-0002-0326-2095
Kristin HolvikDepartment of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0003-3132-2822
Haakon E MeyerDepartment of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0002-3262-8260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on hip fracture prevention in men is limited. In men, physical activity and body mass index were independently and jointly associated with hip fracture risk, with the highest risk among inactive and thin men. Promoting exercise and healthy weight in midlife may reduce fracture burden and support healthy ageing. PURPOSE: Hip fractures predominantly affect older people with frailty. The incidence increases with age, and the number is expected to increase substantially due to population aging. Physical inactivity and low body mass index (BMI) are key modifiable risk factors for hip fractures. This study aimed to explore the associations of physical activity and BMI with long-term hip fracture risk in men.

methodThis prospective cohort study included 12,900 men aged 40-49 years from the Oslo study 1972-1973. A questionnaire assessed physical activity, whereas height and weight were measured. Hip fractures were identified through linkage to a national database. Cox regression calculated adjusted hazard ratios (HR) with 95% confidence intervals (CI) for hip fracture according to physical activity level. A secondary analysis examined a composite variable combining activity level (inactive/active) and BMI (< 22/22-24.9/ ≥ 25 kg/m

resultsDuring 195,384 person-years of follow-up, 1542 men (12%) sustained a hip fracture at a median age of 82 years. Inactive men had a 38% higher risk (HR 1.38 [95% CI 1.16-1.63]) than active men. Active men had a lower hip fracture risk across all categories of BMI, while the greatest risk was found in inactive men with a BMI < 22 kg/m

conclusionsPhysical inactivity and low BMI in midlife were independently associated with increased long-term hip fracture risk. Inactive and thin men had the greatest risk, suggesting that maintaining physical activity in mid-life is important for healthy ageing and independence.

Indexed as

Body Mass IndexExerciseHip FracturesAdultHumansMaleMiddle AgedNorwayProspective StudiesRisk FactorsEpidemiologyExerciseFragility fracturesHip fractureMenPhysical activityPopulation-based studies

Identifiers

PMID41586933
PMCPMC12835019

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.