Evidence map›Paper›PMID 41588204›Full record

ArticleObesity surgery2026

The Weight of a New Heart: Bariatric Surgery after Heart Transplantation and its Clinical Impact.

Laxmi Priya Dongur, Yara Samman, Kush Brahmbhatt, Georgiy Golovko, Kostiantyn Botnar, Feras Shamoun, Cynthia Kassab, Scott Lick, Sarah Samreen

Abstract read
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In one paragraph

Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laxmi Priya DongurDepartment of Surgery, The University of Texas Medical Branch at Galveston, Galveston, United States. ladongur@utmb.edu.
Yara SammanDepartment of Surgery, The University of Texas Medical Branch at Galveston, Galveston, United States.
Kush BrahmbhattDepartment of Surgery, The University of Texas Medical Branch at Galveston, Galveston, United States.
Georgiy GolovkoDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch at Galveston, Galveston, United States.
Kostiantyn BotnarDepartment of Pharmacology and Toxicology, The University of Texas Medical Branch at Galveston, Galveston, United States.
Feras ShamounDepartment of Surgery, The University of Texas Medical Branch at Galveston, Galveston, United States.
Cynthia KassabHouston Methodist DeBakey Heart & Vascular Center, Houston Methodist, Houston, United States.
Scott LickDepartment of Surgery, The University of Texas Medical Branch at Galveston, Galveston, United States.
Sarah SamreenDepartment of Surgery, The University of Texas Medical Branch at Galveston, Galveston, United States.

Funding

NCATS NIH HHS UL1 TR001439
6 · The paper itself

Abstract

introductionSevere obesity (SO) after heart transplantation (HT) worsens long-term graft and patient outcomes. While bariatric surgery (BS) is effective for obesity, its safety and efficacy in heart transplant recipients (HTR) remains poorly defined.

methodsUsing the TrinetX® database, we conducted a retrospective cohort study of adult HTR with BMI ≥ 35 kg/m² between 2000 and 2023. Patients were divided into HTR with post-transplant BS (HTR/BS) and HTR without BS. Propensity score matching adjusted for age, sex, race, ethnicity, and BMI. Primary outcomes were 30-day post-BS complications. Secondary outcomes included mortality, heart failure, coronary artery disease, transplant complications and malignancy up to 5 years following BS.

resultsIn total, 375 patients (HTR/BS − 27; HTR − 348) were analyzed. HTR/BS had no 30-day mortality or major surgical complications. Heart failure rates were significantly lower in HTR/BS cohort at 1 and 3 years, but not at 5 years (13 vs. 24, OR 0.12, p = 0.003; 14 vs. 24, OR 0.14, p = 0.007; 18 vs. 24, OR 0.26, p = 0.1, respectively). At 5 years, transplant complications were significantly lower in HTR/BS vs. HTR (33% vs. 94%, OR 0.1, p = 0.001). Trends toward lower coronary disease were observed in HTR/BS but did not reach significance.

conclusionBariatric surgery is safe in selected HTR and may reduce long-term transplant complications. These findings support BS as a viable intervention for management of obesity post-HT, warranting further prospective validation.

Indexed as

Bariatric SurgeryHeart TransplantationObesity, MorbidPostoperative ComplicationsAdultBody Mass IndexFemaleHeart FailureHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAllograft outcomesBariatric surgeryHeart transplantationImmunosuppressionObesity managementSevere obesity

Identifiers

PMID41588204

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.