SynthesisBMC cancer2026
Associations between whole blood donation and cancer incidence: a systematic review.
Synthesis in BMC cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhole blood (WB) donation has played a critical role in the healthcare system worldwide. However, its long-term safety for donors, particularly regarding the risk of cancer, remains controversial.
objectivesWe systematically reviewed the literature to examine whether WB donation is associated with altered cancer risk among donors.
methodsWe searched PubMed, Scopus, Web of Science, and Google Scholar from September 1990 to December 7, 2024, without time restrictions. Only English-language publications were included. Of 4078 records screened, eleven studies met the eligibility criteria. Study quality was assessed using the Newcastle–Ottawa Scale (NOS), and findings were summarized in Tables and Figures.
resultsMost studies found no significant association between WB donation and overall cancer risk once adjusted for the healthy donor effect (HDE). Reported associations varied across cancer types but were inconsistent and often limited by residual confounding.
conclusionCurrent evidence does not support an increased risk of cancer among WB donors. Further well-designed studies with robust methods to address HDE are warranted to confirm these findings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.