Evidence mapPaperPMID 41588515Full record

ArticleBMC nutrition2026

The association between Nutrient-Rich food score (NRFS) and the odds of lung cancer risk: a case-control study in Iran.

Milad Mohammadzadeh, Fatemeh Abdi, Saeid Hadi, Vahid Hadi, Amin Paydareh, Alireza Bahrami, Melika Mamaghanian, Sharareh Seifi, Ehsan Hejazi

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Article in BMC nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Milad MohammadzadehDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fatemeh AbdiDepartment of Nutrition, Faculty of Nutrition and food science, Tabriz University of Medical Sciences, Tabriz, Iran.
Saeid HadiNutrition and Food health Research Center, Aja University of Medical Science, Tehran, Iran.
Vahid HadiNutrition and Food health Research Center, Aja University of Medical Science, Tehran, Iran.
Amin PaydarehDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Alireza BahramiDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Melika MamaghanianDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Sharareh SeifiResearch Center of Thoracic Oncology (RCTO), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Science, Tehran, Iran. sh_seifi@yahoo.com.
Ehsan HejaziDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Ehsanhejazi@sbmu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA high-quality diet is an important strategy for preventing chronic diseases, including cancer. The Nutrient Rich Food Score (NRFS) is a very useful index that can compare the value of key micronutrients and macronutrients per calorie. The purpose of this study is to investigate the relationship of this index with the risk of lung cancer based on gender for the first time.

methodThis paper is a hospital-based case-control study that includes 135 newly diagnosed lung cancer patient and 237 sex- and age-matched individuals in Iran. A 147-item food frequency questionnaire (147-item-FFQ) was used to assess participants' dietary intake. Multivariate Logistic regression was used to assess the odds ratio (OR) with 95% confidence interval (CI) of lung cancer by the Nutrient Rich Food Score tertiles.

resultsAfter adjustment for potential confounders, a high Nutrient-Rich Food Score was associated with a reduced risk of lung cancer (OR = 0.37, 95% CI: 0.19-0.74). Consistent with the overall result, the protective association remained for men (OR = 0.22, 95% CI: 0.08-0.61), while this relationship failed to reach significant level for women (OR = 0.46, 95% CI: 0.16-1.32).

conclusionThe results showed that a high NRFS is associated with a decrease in lung cancer risk. After stratifying by sex, the association was the same for men, but null among women.

Indexed as

DietDiet qualityLung cancerNutrient rich food

Identifiers

PMID41588515
PMCPMC12896004

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.