Evidence map›Paper›PMID 41588677›Full record

ReviewImmunoHorizons2026

The role of IL-10 in antiviral immune memory development.

Michael C McGee, Wei Luo, Weishan Huang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ImmunoHorizons, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael C McGeeDepartment of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Wei LuoDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States.ORCID 0000-0003-2826-1723
Weishan HuangDepartment of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.

Funding

Markers and regulation of regulatory CD8+ T cells during influenza-induced lung immunopathologyR01AI151139 · NIAID · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI HUANG, WEISHAN · 2021 to 2025
$1.9M
NIH HHS R01 AI151139
6 · The paper itself

Abstract

Viral infections induce heterogeneous memory T and B cell populations that may rapidly recall and provide protection against re-infection. The immunomodulatory cytokine interleukin-10 (IL-10) is well described for its role in restricting immunopathology during viral infection; however, less is known about its role in the development of cellular and humoral immune memory. In this review, we explore the current knowledge of the role of IL-10 in the regulation of antiviral memory T and B cell development. Furthermore, we highlight the importance of the cellular source and timing of IL-10 production in regulating this complex process.

Indexed as

Immunologic MemoryInterleukin-10Virus DiseasesAnimalsB-LymphocytesHumansImmunity, HumoralT-LymphocytesInterleukin-10germinal center reactionhumoral memoryIL-10memory T cellsviral infection

Identifiers

PMID41588677
PMCPMC12821058

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.