ReviewMini reviews in medicinal chemistry2026
Unraveling the Multifunctional Therapeutic Potential of Topsentin: A Marine-derived Versatile Scaffold.
Review in Mini reviews in medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
Funding
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Abstract
Natural products (NPs) have long served as a rich inspirational source for drug discovery and development, offering diverse chemical structures and biological activities. Among these, topsentin, a marine alkaloid derived from marine sponges, has emerged as a promising scaffold due to its remarkable pharmacological properties and structural versatility. This review explores the significance of topsentin and its derivatives in drug discovery efforts. It discusses the diverse biological activities of topsentin and its analogs, including anticancer, antimicrobial, anti-inflammatory, and antiviral properties, highlighting their potential therapeutic applications. Moreover, it also focuses on the structural features of topsentin that contribute to its pharmacological profile, emphasizing its importance in the design and development of novel therapeutic agents. Structural modifications and synthetic strategies employed to enhance the pharmacological properties of topsentin derivatives are also discussed. Overall, this review underscores the significance of topsentin as a promising scaffold in drug discovery.
Indexed as
Identifiers
41588766What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.