Evidence map›Paper›PMID 41590298›Full record

ReviewBiosensors2026

Wearable Sensing Systems for Multi-Modal Body Fluid Monitoring: Sensing-Combination Strategy, Platform-Integration Mechanism, and Data-Processing Pattern.

Manqi Peng, Yuntong Ning, Jiarui Zhang, Yuhang He, Zigan Xu, Ding Li, Yi Yang, Tian-Ling Ren

Abstract readReview
In one paragraph

Review in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Manqi PengSchool of Integrated Circuit, Tsinghua University, Beijing 100084, China.
Yuntong NingSchool of Integrated Circuit, Tsinghua University, Beijing 100084, China.
Jiarui ZhangSchool of Integrated Circuit, Tsinghua University, Beijing 100084, China.ORCID 0009-0009-9934-9838
Yuhang HeSchool of Integrated Circuit, Tsinghua University, Beijing 100084, China.
Zigan XuSchool of Integrated Circuit, Tsinghua University, Beijing 100084, China.
Ding LiSchool of Integrated Circuit, Tsinghua University, Beijing 100084, China.
Yi YangSchool of Integrated Circuit, Tsinghua University, Beijing 100084, China.ORCID 0000-0002-1161-9488
Tian-Ling RenSchool of Integrated Circuit, Tsinghua University, Beijing 100084, China.

Funding

Beijing Natural Science Foundation QY25057the National Key R&D Program 2022YFB3204100the National Natural Science Foundation of China U20A20168
6 · The paper itself

Abstract

Wearable multi-modal body fluid monitoring enables continuous, non-invasive, and context-aware assessment of human physiology. By integrating biochemical and physical information across multiple modalities, wearable systems overcome the limitations of single-marker sensing and provide a more holistic view of dynamic health states. This review offers a system-level overview of recent advances in multi-modal body fluid monitoring, structured into three hierarchical dimensions. We first examine sensing-combination strategies such as multi-marker analysis within single fluids, coupling biochemical signals with bioelectrical, mechanical, or thermal parameters, and emerging multi-fluid acquisition to improve analytical accuracy and physiological relevance. Next, we discuss platform-integration mechanisms based on biochemical, physical, and hybrid sensing principles, along with monolithic and modular architectures enabled by flexible electronics, microfluidics, microneedles, and smart textiles. Finally, the data-processing patterns are analyzed, involving cross-modal calibration, machine learning inference, and multi-level data fusion to enhance data reliability and support personalized and predictive healthcare. Beyond summarizing technical advances, this review establishes a comprehensive framework that moves beyond isolated signal acquisition or simple metric aggregation toward holistic physiological interpretation. It guides the development of next-generation wearable multi-modal body fluid monitoring systems that overcome the challenges of high integration, miniaturization, and personalized medical applications.

Indexed as

Biosensing TechniquesBody FluidsWearable Electronic DevicesDigital HealthHumansMonitoring, Physiologicbiochemical sensingbody fluidhealth monitorintegrated systemmulti-modalwearable

Identifiers

PMID41590298
PMCPMC12839173

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.