Evidence map›Paper›PMID 41590618›Full record

ArticleMetabolites2025

Metabolomic Signatures of Physical Function and Functional Trajectories in Older Adults: Insights from the ENRGISE Clinical Trial.

David H Lynch, Liubov Arbeeva, Susan C J Sumner, Blake R Rushing, John A Batsis, Amanda E Nelson, Roger A Fielding

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David H LynchDivision of Geriatric Medicine, Center for Aging and Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-2512-9367
Liubov ArbeevaThurston Arthritis Research Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Susan C J SumnerNutrition Research Institute, Department of Nutrition, University of North Carolina, Kannapolis, NC 28081, USA.
Blake R RushingNutrition Research Institute, Department of Nutrition, University of North Carolina, Kannapolis, NC 28081, USA.ORCID 0000-0002-8662-3270
John A BatsisDivision of Geriatric Medicine, Center for Aging and Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-0845-4416
Amanda E NelsonThurston Arthritis Research Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-9344-7877
Roger A FieldingMetabolism and Basic Biology of Aging Directive, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA.

Funding

UNC Core Center for Clinical ResearchP30AR072580 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Amanda E Nelson · 2019 to 2026
$6.1M
Mentoring in Patient Oriented Research in OsteoarthritisK24AR081368 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Amanda E Nelson · 2022 to 2026
$916k
Clin-STAR Coordinating Center CS22005NIAMS NIH HHS K24 AR081368NIAMS NIH HHS P30 AR072580
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aginggerosciencemetabolomoicsphysical function

Identifiers

PMID41590618
PMCPMC12844133

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.