Evidence map›Paper›PMID 41590655›Full record

ArticleMetabolites2026

Metabolic Outcomes in Bariatric/Metabolic Surgery Individuals: Impact of Metabolic Health Definition, Type of Surgery, and Follow-Up Duration-An Observational, Retrospective Study.

Anna Pluemacher, Cláudia Camila Dias, Bárbara Peleteiro, Denise Pinheiro, Paula Freitas, Eduardo Lima, Alexandra Leitão, Elisabete Martins, Maria João Martins

Abstract read
In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna PluemacherFaculty of Nutritional Sciences, University of Potsdam, 14476 Potsdam, Germany.
Cláudia Camila DiasKnowledge Management Unit, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0001-9356-3272
Bárbara PeleteiroCentro de Epidemiologia Hospitalar, Unidade Local de Saúde São João, 4200-319 Porto, Portugal.ORCID 0000-0002-0579-9988
Denise PinheiroUnit of Biochemistry, Department of Biomedicine, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Paula FreitasFaculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Eduardo LimaFaculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Alexandra LeitãoDepartamento de Medicina Interna, Unidade Local de Saúde de Barcelos/Esposende, 4754-909 Barcelos, Portugal.
Elisabete MartinsRISE-Health, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0002-6944-2953
Maria João MartinsUnit of Biochemistry, Department of Biomedicine, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0002-3560-3261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is no standardized definition for metabolic health. Overweight and obesity are often linked to metabolic dysfunction. Bariatric surgery promotes body weight loss and cardiometabolic health improvement.

objectiveWe aim to characterize metabolic health using distinct definitions and evaluate anthropometric and cardiometabolic features, both before and after different surgery procedures.

methodsWe studied 3313 individuals from CRI-O [Porto, PT; BMI 39.56 (42.60; 46.20) kg/m

resultsBaseline metabolic health classification and metabolically unhealthy phenotype (MUH) post-surgery prevalence decrease show substantial variability depending on the definition used. Unlike relative body weight loss, the altered metabolic feature number in MUH remains unchanged. Changes in MUH prevalence do not reflect body weight loss, nor does the variation in MUH percentage fully align with changes in altered metabolic features. Blood pressure, C-reactive protein, antihypertensive medication, and HOMA-IR are key contributors to baseline MUH. Post-surgical changes in body weight, lipid profile, and C-reactive protein vary by procedure. RYGB yields greater weight loss and more often improves cardiometabolic markers. However, post-operative metabolic phenotype is independent of surgery type.

conclusionsMetabolic health phenotypes pre- and post-surgery vary by definition, and the latter are not solely driven by weight loss or surgery type. In this cohort, RYGB shows the strongest beneficial impact.

Indexed as

bariatric surgerygastric bandmetabolically healthy phenotypemetabolically unhealthy phenotypemetabolic health phenotypesobesityoverweightRoux-en-Y gastric bypasssleeve gastrectomy

Identifiers

PMID41590655
PMCPMC12843696

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.