Itaconate Promotes Cold Adaptation and Myocardial Protection by Enhancing Brown Adipose Tissue Metabolism.

Zilong Geng, Xing Liu, Xiao Cheng, Shizhan Xu, Jin Zhang, Ao Tan, Shun Song, Shasha Zhang

Abstract read

In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zilong GengKey Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Department of Cardiovascular Surgery, Xin Hua Hospital, Department of Physical Education, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

Xing LiuBasic Medical Research Center, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou 325027, China.

Xiao ChengCollege of Biological and Chemical Engineering, Jiaxing University, Jiaxing 314001, China.

Shizhan XuKey Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Department of Cardiovascular Surgery, Xin Hua Hospital, Department of Physical Education, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

Jin ZhangKey Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Department of Cardiovascular Surgery, Xin Hua Hospital, Department of Physical Education, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

Ao TanKey Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Department of Cardiovascular Surgery, Xin Hua Hospital, Department of Physical Education, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

Shun SongKey Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Department of Cardiovascular Surgery, Xin Hua Hospital, Department of Physical Education, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

Shasha ZhangKey Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Department of Cardiovascular Surgery, Xin Hua Hospital, Department of Physical Education, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0009-0004-5516-9644

Funding

National Natural Science Foundation of China 32200926SJTU STAR Award YG2025QNB40 and YG2023QNB13Young Scientific Research Special Fund KLSB2022QN-03Young Teacher initiation program 20X100040018

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brown adipose tissueitaconatemetabolismmyocardial injury

Identifiers

PMID41590674

DOI10.3390/metabo16010066

PMCPMC12844064

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.