ArticleMarine drugs2026
Discovery of RUVBL1 as a Target of the Marine Alkaloid Caulerpin via MS-Based Functional Proteomics.
Alessandra Capuano, Gilda D'Urso, Lucia Capasso, Emilio Brancaccio, Erica Gazzillo, Marianna Carbone, Ernesto Mollo, Gianluigi Lauro, Maria Giovanna Chini, Giuseppe Bifulco and 2 more
Abstract read
In one paragraphArticle in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
12 authors.
Alessandra CapuanoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 80084 Fisciano, Italy.
Gilda D'UrsoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 80084 Fisciano, Italy.ORCID 0000-0002-4407-2781 Lucia CapassoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via De Crecchio 7, 80138 Naples, Italy.ORCID 0000-0002-0678-6329 Emilio BrancaccioDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 80084 Fisciano, Italy.
Erica GazzilloDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 80084 Fisciano, Italy.
Marianna CarboneInstitute of Biomolecular Chemistry, National Research Council of Italy, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.
Ernesto MolloInstitute of Biomolecular Chemistry, National Research Council of Italy, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0001-7379-1788 Gianluigi LauroDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 80084 Fisciano, Italy.ORCID 0000-0001-5065-9717 Maria Giovanna ChiniDepartment of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Isernia, Italy.
Giuseppe BifulcoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 80084 Fisciano, Italy.
Angela NebbiosoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via De Crecchio 7, 80138 Naples, Italy.ORCID 0000-0001-5374-3527 Agostino CasapulloDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 80084 Fisciano, Italy.ORCID 0000-0002-2310-9426 Funding
european Union PRIN PNRR 2022 "P2022CKMPWEuropean Union PNRR-MCNT2-2023-123777474University of Salerno ORSA238540
6 · The paper itselfAbstract
Marine flora is a significant source of bioactive metabolites. These compounds have been demonstrated to have outstanding bioactivity and biocompatibility, enabling their use in various therapeutic applications. Therefore, examining the biological potential of marine natural compounds remains important, with particular emphasis on their interaction profiles to identify the macromolecular partners they can modulate. This study focused on the interactome profiling of the marine alkaloid caulerpin (CAU), isolated from the alga
Indexed as
AlkaloidsAntineoplastic AgentsCarrier ProteinsCaulerpaAquatic OrganismsCell Line, TumorHumansIndolesMass SpectrometryProteomicsAlkaloidsAntineoplastic AgentsCarrier ProteinscaulerpinIndolesalkaloidcaulerpinlimited proteolysismass spectrometryRUVB-like1
Identifiers
PMID41590734
PMCPMC12842763
What Socratic holds
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