Evidence map›Paper›PMID 41590872›Full record

ArticleJournal of cardiovascular development and disease2026

Fontan Route Remodeling over Time: A Longitudinal Quantitative 3D Case Series.

Raquel Dos Santos, Amartya Dave, Mohammed Usmaan Siddiqi, Aashi Dharia, Deqa Muse, Junsung Kim, Kameel Khabaz, Nhung Nguyen, Luka Pocivavsek, Narutoshi Hibino

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Raquel Dos SantosSection of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.ORCID 0009-0001-6343-9200
Amartya DaveSchool of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-3282-3346
Mohammed Usmaan SiddiqiMolecular, Cellular & Developmental Biology, Pierson College, Yale University, New Haven, CT 06520, USA.ORCID 0009-0002-1954-2937
Aashi DhariaSection of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.
Deqa MuseSection of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.
Junsung KimSection of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-9117-4628
Kameel KhabazDepartment of Radiology, Division of Interventional Radiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-3164-6133
Nhung NguyenSection of Vascular Surgery, Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.
Luka PocivavsekSection of Vascular Surgery, Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.
Narutoshi HibinoSection of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, IL 60637, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fontan patients experience anatomical remodeling over time, yet the mechanisms driving these changes remain unclear. This study aimed to characterize full-route Fontan remodeling and evaluate whether observed morphological changes arise from somatic growth alone or from the combined influence of conduit properties, surgical design, thoracic anatomy, and mechanical forces. Five Fontan patients (four extracardiac, one lateral tunnel) underwent analysis using two MRI-derived 3D models obtained between 1 and 4 years apart. Directional displacement was assessed using 3D shape overlays, surface geometry was quantified using the Koenderink Shape Index (KSI), and patient-specific growth mapping estimated localized tissue dynamics. Statistical analyses included a one-sample

Indexed as

3D modelingcardiovascular biomechanicsconduit propertiescongenital heart diseaseFontan proceduregrowth mappingremodelingshape analysissingle-ventricle physiologysomatic growth

Identifiers

PMID41590872
PMCPMC12842021

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.