Evidence map›Paper›PMID 41590984›Full record

ArticleSports (Basel, Switzerland)2026

Effects of a 6-Week Intermittent Hypoxia-Hyperoxia Exposure Program on Blood Pressure, Respiratory Function, Cardiac Autonomic Nervous Activity and CRP Levels in Older Adults: A Randomized Clinical Trial.

Arturo Ladriñán-Maestro, Alberto Sánchez-Sierra, María Herrera-Gómez-Platero, Jorge Sánchez-Infante

Abstract read
In one paragraph

Article in Sports (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arturo Ladriñán-MaestroPain, Mental Health, Exercise and Technology Research Group (PAIN + MET), Faculty of Physical Therapy and Nursing, Universidad de Castilla-La Mancha, 45071 Toledo, Spain.ORCID 0009-0006-8504-0715
Alberto Sánchez-SierraGrupo de Investigación en Fisioterapia Toledo (GIFTO), Facultad de Fisioterapia y Enfermería, Universidad de Castilla-La Mancha, 45071 Toledo, Spain.ORCID 0000-0002-1645-8417
María Herrera-Gómez-PlateroInstitute of Health and Sport Sciences, Faculty of Health Science, Universidad Francisco de Vitoria, 28223 Madrid, Spain.ORCID 0009-0001-3102-5484
Jorge Sánchez-InfanteGrupo de Investigación en Fisioterapia Toledo (GIFTO), Facultad de Fisioterapia y Enfermería, Universidad de Castilla-La Mancha, 45071 Toledo, Spain.ORCID 0000-0002-0840-6000

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe aim of this study is to objectively evaluate the effects of a six-week intermittent hypoxic-hyperoxic exposure program on blood pressure, respiratory function, cardiac autonomic nervous activity and C Reactive Protein levels in older adults. MATERIALS AND

methodsA double-blinded randomized controlled clinical trial was conducted on twenty-two older adults. Heart rate variability, respiratory function, blood pressure, C Reactive Protein levels and oxygen saturation were measured at two time points: baseline and after 6 weeks of treatment.

resultsThe maximal inspiratory pressure variable increased significantly in the EG (+7.50 ± 1.72 cmH2O,

conclusionsSix weeks of intermittent hypoxic-hyperoxic exposure was associated with trends toward improvements in blood pressure, respiratory function, cardiac autonomic nervous activity, and C Reactive Protein levels, compared with a placebo application of the same therapy.

Indexed as

autonomic cardiac controlintermittent hypoxiaphysiotherapyrespiratory muscle strengthrespiratory rehabilitation

Identifiers

PMID41590984
PMCPMC12846263

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.