Evidence map›Paper›PMID 41591231›Full record

ArticleTropical medicine and infectious disease2026

Analysis of the Short- and Long-Term Immune Response in BALB/c Mice Immunized with Total

Mara Gutiérrez-Sánchez, Maria de la Luz Ortega-Juárez, María Maricela Carrasco-Yépez, Rubén Armando Herrera-Ceja, Itzel Berenice Rodríguez-Mera, Saúl Rojas-Hernández

Abstract read
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In one paragraph

Article in Tropical medicine and infectious disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mara Gutiérrez-SánchezLaboratorio de Inmunobiología Molecular y Celular, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City C. P. 11340, Mexico.ORCID 0000-0001-8789-370X
Maria de la Luz Ortega-JuárezLaboratorio de Inmunobiología Molecular y Celular, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City C. P. 11340, Mexico.ORCID 0000-0003-0903-5691
María Maricela Carrasco-YépezLaboratorio de Microbiología, Grupo CyMA, Unidad de Investigación Interdisciplinaria en Ciencias de la Salud y la Educación, UNAM FES Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla de Baz C. P. 54090, Mexico.ORCID 0000-0001-6290-3393
Rubén Armando Herrera-CejaLaboratorio de Inmunobiología Molecular y Celular, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City C. P. 11340, Mexico.ORCID 0000-0003-4330-8737
Itzel Berenice Rodríguez-MeraLaboratorio de Microbiología, Grupo CyMA, Unidad de Investigación Interdisciplinaria en Ciencias de la Salud y la Educación, UNAM FES Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla de Baz C. P. 54090, Mexico.ORCID 0009-0001-5536-8502
Saúl Rojas-HernándezLaboratorio de Inmunobiología Molecular y Celular, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City C. P. 11340, Mexico.ORCID 0000-0002-1936-2664

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThis study evaluated short- and long-term immune protection in BALB/c mice (20 mice per group) immunized intranasally with total

resultsImmunization conferred complete (100%) survival in the 24 h group and 60% protection in the 3-month group, whereas all control mice died. Immunoblotting showed that IgA and IgG antibodies recognized major

conclusionsIntranasal immunization with

Indexed as

cholera toxinimmunizationNaegleria fowlerinasal-associated lymphoid tissuenasal passages

Identifiers

PMID41591231
PMCPMC12846575

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.