ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Real-Time and High-Resolution NIR-II-L Imaging of Netrin-1-Mediated Neurovascular Coupling Driven by Dose-Dependent Electroacupuncture.
Yicong Wang, Zi-Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang and 6 more
Abstract read
In one paragraphArticle in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
16 authors.
Yicong WangDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0005-5501-7998 Zi-Han ChenDepartment of Chemistry, College of Smart Materials and Future Energy, New Cornerstone Science Laboratory, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and Ichem, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-3322-1489 Jiajia LiDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Wei HuDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-8813-633X Ying CaoSuzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine Gynecology Department, Suzhou City, Jiangsu Province, China.
Xiaoyu TongDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0008-2338-1367 Yuze YangDepartment of Medical Physics, Shanghai Proton and Heavy lon Center, Shanghai, China.
Yuehao WangDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Yan XiaoDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0009-2281-4375 Wenhao GaoDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0007-7928-2678 Yuning ChenReproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Yuyan HouDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Fan ZhangDepartment of Chemistry, College of Smart Materials and Future Energy, New Cornerstone Science Laboratory, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials and Ichem, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-7886-6144 Yi FengDepartment of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-7156-6023 Funding
China Postdoctoral Science Foundation 2025M780913Development Project of Shanghai Peak Disciplines-Integrated Chinese and Western Medicine 20180101Innovative Research Team of High-Level Local Universities in ShanghaiNational Natural Science Foundation of China 81973945National Natural Science Foundation of China 82174497National Natural Science Foundation of China 82505741
6 · The paper itselfAbstract
Accumulating evidence implicates that disrupted ovarian neurovascular coupling is a vital driver for polycystic ovary syndrome. Electroacupuncture (EA), as a form of peripheral neuromodulation, offers a potential therapeutic avenue to restore this coupling and improve ovarian function. However, how neural regulation leads to vascular changes remains unclear. Conventional histological and imaging methods cannot capture either immediate or long-term effects of EA on neurovascular dynamics, as they are limited by the lack of real-time and continuous in vivo visualization. Here, core-shell lanthanide nanocrystals α-NaYbF
Indexed as
ElectroacupunctureNetrin-1Neurovascular CouplingOvaryAnimalsFemaleMiceNetrin-1NIR‐II‐L imagingoptical theranosticsovarian neurovascular couplingreal‐time imaging
Identifiers
PMID41591262
PMCPMC13045393
What Socratic holds
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LicenceCC BY
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