Evidence map›Paper›PMID 41591266›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Chloroplast Stress Signals Orchestrate Epidermis-Specific Remodeling of Mitochondria and ER Under High Light.

Evan R Angelos, Hee-Seung Choi, Jingzhe Guo, Andrea A Zanini, Tessa M Burch-Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Evan R AngelosInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.
Hee-Seung ChoiInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.
Jingzhe GuoInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.
Andrea A ZaniniDonald Danforth Plant Science Center, St. Louis, Missouri, USA.
Tessa M Burch-SmithDonald Danforth Plant Science Center, St. Louis, Missouri, USA.
Emily SnyderInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.
Matthew PartInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.
Wilhelmina van de VenInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.
Manhoi HurInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.
Gerd Ulrich BalckeDepartment of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany.
Alain TissierDepartment of Cell and Metabolic Biology, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany.
Quanqing ZhangInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.
Katayoon DeheshInstitute For Integrative Genome Biology and Department of Botany and Plant Sciences, University of California, Riverside, California, USA.ORCID https://orcid.org/0000-0002-9312-8032

Funding

National Science Foundation NSF2104365NIGMS NIH HHS R01GM107311-8
6 · The paper itself

Abstract

Environmental stress demands precise coordination among organelles to maintain cellular homeostasis. In Arabidopsis, high light (HL) exposure triggers chloroplast-dependent remodeling of mitochondrial and endoplasmic reticulum (ER) morphology specifically in adaxial and abaxial epidermal cells, but not in mesophyll cells. Live-cell imaging reveals that HL rapidly suppresses mitochondrial motility, followed by fusion-driven elongation and ER cisternal expansion. Inhibition of photosynthetic, but not mitochondrial, electron transport abolishes these changes, confirming chloroplast activity as the upstream trigger. Pharmacological analyses show that exogenous H

Indexed as

ArabidopsisChloroplastsEndoplasmic ReticulumLightMitochondriaPlant EpidermisStress, PhysiologicalArabidopsis ProteinsHydrogen PeroxideSignal TransductionArabidopsis ProteinsHydrogen Peroxidechloroplast signalingepidermal organelle dynamicshigh light stressMiro1mitochondrial‐ER remodelingorganelle plasticity

Identifiers

PMID41591266
PMCPMC13042555

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.