Article in American journal of physiology. Heart and circulatory physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Bowen YangResearch Imaging Institute, University of Texas Health Science Center, San Antonio, Texas, United States.ORCID 0000-0002-5272-8349
Daniel A AdekunbiBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, Texas, United States.ORCID 0000-0001-5456-3392
Hillary F HuberSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, United States.ORCID 0000-0001-9734-427X
Raechel CamonesBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, Texas, United States.
Jinqi LiResearch Imaging Institute, University of Texas Health Science Center, San Antonio, Texas, United States.
Alexander J MoodyBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, Texas, United States.
Angelica M RiojasResearch Imaging Institute, University of Texas Health Science Center, San Antonio, Texas, United States.ORCID 0000-0002-4918-407X
Cun LiDepartment of Animal Science, University of Wyoming, Laramie, Wyoming, United States.
Shannan Hall-UrsoneSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, United States.
Patrice FrostSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, United States.
Thomas C RegisterCenter for Precision Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.ORCID 0000-0002-4078-0166
Laura A CoxCenter for Precision Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.ORCID 0000-0002-8836-3783
Peter W NathanielszDepartment of Animal Science, University of Wyoming, Laramie, Wyoming, United States.
Adam B SalmonBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center, San Antonio, Texas, United States.ORCID 0000-0002-1475-7843
Geoffrey D ClarkeResearch Imaging Institute, University of Texas Health Science Center, San Antonio, Texas, United States.ORCID 0000-0003-4559-6437
Funding
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Womb to Tomb: Developmental Programming and Aging Interactions in PrimatesU19AG057758 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CLARKE, GEOFFREY DAVID, COX, LAURA A · 2018 to 2024
$13.2M
American Heart Association (AHA) 24PRE1191693HHS | NIH | National Institute on Aging (NIA) U19AG057758NIA NIH HHS U19 AG057758NIH HHS P51 OD011133ODCDC CDC HHS P51 OD011133
6 · The paper itself
Abstract
Women threatening premature delivery receive synthetic glucocorticoids (sGC) to reduce offspring neonatal respiratory distress. Evidence linking prenatal sGC exposures to adverse cardiovascular outcomes is accumulating. We studied adult baboons, which had been exposed in utero to sGC equivalent to a human therapeutic dose, and compared with age-matched saline-exposed controls (CTR). Magnetic resonance imaging was performed in middle-aged male offspring (∼10.5 yr) and in both sexes at old age (∼16.5 yr) to assess heart structure, function, and paracardial adipose thickness (PAT). Postmortem left ventricular (LV) tissues were analyzed for mitochondrial electron transport chain complex activities and protein expression. In sGC versus CTR males, LV end-systolic (ESSI) and end-diastolic (EDSI) sphericity indexes increased with age (ESSI:
Indexed as
GlucocorticoidsHeart VentriclesPrenatal Exposure Delayed EffectsVentricular Function, LeftVentricular RemodelingAge FactorsAnimalsDevelopmental Origins of Health and DiseaseFemaleGlobal Longitudinal StrainMaleMitochondria, HeartPapioPregnancyGlucocorticoidscardiac functiondevelopmental programmingmitochondrial functionnonhuman primatessynthetic glucocorticoids
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Prenatal glucocorticoid exposure programs long-term left ventricular metabolism, function, and remodeling in baboons. · full record | Socratic